Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 3/20 | 0.36 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | MITF | O75030 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8328869 | 0.98 | CHRM2 (0.44) | CHRM2ACHESCN8AALDH1A1KDM4E | |
| SCHEMBL8325662 | 0.97 | CHRM2 (0.46) | CHRM2ACHESCN8AALDH1A1KDM4E | |
| SCHEMBL8324185 | 0.92 | CHRM2 (0.39) | CHRM2ACHESCN8AALDH1A1KDM4E | |
| SCHEMBL8330575 | 0.89 | MEN1 (0.35) | CHRM2ACHESCN8AALDH1A1KDM4E | |
| SCHEMBL8322051 | 0.87 | ALDH1A1 (0.42) | ALDH1A1KDM4EPOLBGAAL3MBTL1 | |
| SCHEMBL8327788 | 0.76 | MEN1 (0.37) | CHRM2ACHESCN8AALDH1A1KDM4E | |
| SCHEMBL8329466 | 0.76 | NRP1 (0.33) | ALDH1A1KDM4EGAAL3MBTL1TP53 | |
| SCHEMBL8619931 | 0.74 | CHRM2 (0.47) | CHRM2ACHESCN8AALDH1A1L3MBTL1 | |
| SCHEMBL8327285 | 0.73 | HDAC3 (0.34) | ALDH1A1POLBGAAHDAC3HDAC1 | |
| SCHEMBL8327173 | 0.71 | PRKAA2 (0.42) | ACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| US-5736550-A | TREATMENT OF GASTROINTESTINAL TRACT DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |