Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | TOP1 | P11387 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | STAT1 | P42224 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8793929 | 0.82 | L3MBTL1 (0.49) | L3MBTL1SCN9AKCNH2SCN5AHPGD | |
| SCHEMBL12522822 | 0.78 | L3MBTL1 (0.52) | L3MBTL1HPGDLMNAPKMALDH1A1 | |
| SCHEMBL8619461 | 0.77 | L3MBTL1 (0.46) | L3MBTL1SCN9AKCNH2SCN5AHPGD | |
| SCHEMBL23585046 | 0.77 | L3MBTL1 (0.59) | L3MBTL1HPGDLMNAPKMALDH1A1 | |
| SCHEMBL9185538 | 0.76 | L3MBTL1 (0.50) | L3MBTL1HPGDLMNAPKMALDH1A1 | |
| SCHEMBL9188610 | 0.76 | L3MBTL1 (0.56) | L3MBTL1HPGDLMNAPKMALDH1A1 | |
| SCHEMBL12939880 | 0.76 | L3MBTL1 (0.58) | L3MBTL1HPGDLMNAPKMALDH1A1 | |
| SCHEMBL7212283 | 0.76 | RAB9A (0.62) | L3MBTL1PKMALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL9188543 | 0.76 | L3MBTL1 (0.58) | L3MBTL1HPGDLMNAPKMALDH1A1 | |
| SCHEMBL27960801 | 0.76 | L3MBTL1 (0.58) | L3MBTL1HPGDLMNAPKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5767121-A | ANTIINFLAMMATORY AND -ARTHRITIC AGENTS; ANTIPYRETICS; ANALGESICS; ADHESION PROTEIN EXPRESSION AND CYCLOXYGENASE AND 5-LIPOXYGENASE INHIBITORS; IMMUNOSUPPRESSANTS AND -MODULATORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-06-16 | — | — | US | disclosed |