SCHEMBL6759877

SCHEMBL6759877

O=S(O)Oc1ccccc1OS(=O)O

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
CA12 O43570 1/20 0.35
CA4 P22748 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
CA14 Q9ULX7 1/20 0.35
TSHR P16473 2/20 0.33
TP53 P04637 1/20 0.33
ELANE P08246 1/20 0.33
G6PD P11413 1/20 0.33
MAPT P10636 3/20 0.31
KDM4E B2RXH2 3/20 0.31
HPGD P15428 3/20 0.31
HSD17B10 Q99714 3/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
ALDH1A1 P00352 2/20 0.31
KMT2A Q03164 1/20 0.31
ESR1 P03372 1/20 0.31
ITGB3 P05106 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzoquinone SCHEMBL11128432 0.89 ALDH1A1 (0.35) MAPTHSD17B10SMN1; SMN2ALDH1A1KMT2A
SCHEMBL2911000 0.85 CA2 (0.48) CA1CA2CA12CA4CA14
SCHEMBL31618991 0.84 PARP10 (0.41) MAPTKDM4EHPGDSMN1; SMN2ALDH1A1
SCHEMBL29721153 0.84 TSHR (0.41) TSHRMAPTKDM4ESMN1; SMN2KMT2A
SCHEMBL18632044 0.84 PARP10 (0.41) MAPTKDM4EHPGDSMN1; SMN2ALDH1A1
SCHEMBL497623 0.84 TSHR (0.41) TSHRMAPTKDM4ESMN1; SMN2KMT2A
SCHEMBL778805 0.80 L3MBTL1 (0.47) TSHRMAPTKDM4EHPGDHSD17B10
SCHEMBL8748075 0.80 ALDH1A1 (0.53) CA1CA2TSHRMAPTHPGD
SCHEMBL8620189 0.80 ALDH1A1 (0.49) TSHRKDM4EHPGDHSD17B10ALDH1A1
SCHEMBL8009306 0.79 ALDH1A1 (0.47) TSHRKDM4EHPGDHSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4340690-A Cyclic organo carbonate and sulfite coupling agents for living polymers of conjugated dienes THE GOODYEAR TIRE & RUBBER COMPANY (US) 1982-07-20 US claimed
US-4301258-A OF BROADENED MOLECULAR WEIGHT DISTRIBUTION; HIGH IMPACT PLASTICS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1981-11-17 US claimed
US-6726795-B1 COMPOSITION COMPRISING 2-CYANOACRYLATE MONOMER, METALLOCENE, PHOTOINITIATOR, SULFUR-CONTAINING COMPOUND, AND POLYMETHYL METHACRYLATE Henkel IP & Holding GmbH (DE) 2004-04-27 US disclosed
EP-0579476-B1 Cyanoacrylate adhesives with improved cured thermal properties LOCTITE CORP (US) 1996-01-24 EP disclosed
US-5328944-A Heat resistant polymers LOCTITE CORPORATION (US) 1994-07-12 US disclosed
EP-0579476-A1 Cyanoacrylate adhesives with improved cured thermal properties LOCTITE CORPORATION (US) 1994-01-19 EP disclosed
US-4340690-A Cyclic organo carbonate and sulfite coupling agents for living polymers of conjugated dienes THE GOODYEAR TIRE & RUBBER COMPANY (US) 1982-07-20 US disclosed
US-4301258-A OF BROADENED MOLECULAR WEIGHT DISTRIBUTION; HIGH IMPACT PLASTICS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1981-11-17 US disclosed