Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 4/20 | 0.48 |
| ▸ | RARA | P10276 | 3/20 | 0.48 |
| ▸ | RARG | P13631 | 9/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8570459 | 0.91 | RARA (0.55) | IKBKBRARARARGRARBMEN1 | |
| SCHEMBL8397932 | 0.88 | IKBKB (0.48) | IKBKBRARARARGRARBMEN1 | |
| SCHEMBL8397840 | 0.84 | IKBKB (0.47) | IKBKBRARARARGRARBS1PR1 | |
| SCHEMBL6033341 | 0.83 | IKBKB (0.49) | IKBKBRARARARGRARBMEN1 | |
| SCHEMBL6033010 | 0.82 | IKBKB (0.48) | IKBKBRARARARGRARBMEN1 | |
| SCHEMBL8433279 | 0.81 | RARA (0.62) | IKBKBRARARARGRARBMEN1 | |
| SCHEMBL6033012 | 0.81 | IKBKB (0.47) | IKBKBRARARARGRARBMEN1 | |
| SCHEMBL8394251 | 0.81 | IKBKB (0.56) | IKBKBRARARARGRARBALDH1A1 | |
| SCHEMBL8399153 | 0.80 | IKBKB (0.58) | IKBKBRARARARGRARBMEN1 | |
| SCHEMBL7753722 | 0.80 | RARA (0.53) | IKBKBRARARARGRARBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0679631-B1 | Biaromatic acetylated, an adamantyl group containing compounds, pharmaceutical and cosmetic compositions containing them and their use | CIRD GALDERMA (FR) | 1998-05-06 | — | — | EP | claimed |