Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | ACE | P12821 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8621139 | 0.85 | ITGB3 (0.37) | ALDH1A1MAPK1NPSR1LMNAMEN1 | |
| Hydrochloric Acid SCHEMBL8619234 | 0.84 | ITGB3 (0.36) | ALDH1A1MAPK1NPSR1LMNAMEN1 | |
| SCHEMBL7371949 | 0.83 | ACE (0.35) | ALDH1A1CYP19A1ACELMNAMEN1 | |
| SCHEMBL7374011 | 0.79 | DPP4 (0.36) | ALDH1A1CYP19A1SMN1; SMN2OPRM1 | |
| SCHEMBL8619349 | 0.78 | ACE2 (0.36) | CYP19A1 | |
| Hydrochloric Acid SCHEMBL8621091 | 0.78 | ITGB3 (0.34) | ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL8103481 | 0.77 | ITGB3 (0.35) | ALDH1A1CYP19A1ACEMEN1KMT2A | |
| SCHEMBL8618344 | 0.75 | ITGB3 (0.35) | — | |
| SCHEMBL7375308 | 0.75 | ITGB3 (0.32) | ACE | |
| SCHEMBL8619325 | 0.75 | MC4R (0.38) | MC4RALDH1A1CYP19A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852045-A | Fibrinogen receptor antagonists | MERCK & CO., INC. (US) | 1998-12-22 | — | — | US | disclosed |