Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | PREP | P48147 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7365778 | 0.89 | ITGB3 (0.45) | ACE2FKBP1A | |
| SCHEMBL8103481 | 0.88 | ITGB3 (0.35) | ACHECYP19A1 | |
| SCHEMBL7371949 | 0.83 | ACE (0.35) | CYP2C9CYP2D6ACHECYP19A1CYP3A4 | |
| SCHEMBL8619473 | 0.81 | FAAH (0.30) | — | |
| Hydrochloric Acid SCHEMBL7368927 | 0.80 | ITGB3 (0.34) | — | |
| SCHEMBL8620398 | 0.78 | MC4R (0.33) | CYP19A1 | |
| SCHEMBL7374011 | 0.78 | DPP4 (0.36) | ACHECYP19A1 | |
| SCHEMBL8621139 | 0.77 | ITGB3 (0.37) | — | |
| Hydrochloric Acid SCHEMBL8619234 | 0.77 | ITGB3 (0.36) | — | |
| SCHEMBL8621118 | 0.76 | ITGB3 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852045-A | Fibrinogen receptor antagonists | MERCK & CO., INC. (US) | 1998-12-22 | — | — | US | disclosed |
| US-5502165-A | AMIDATION OF CARBOXY COMPOOUND WITH AMINE IN WATER AND SOLVENT | MERCK & CO., INC. (US) | 1996-03-26 | — | — | US | disclosed |