Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 7/20 | 0.42 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8621319 | 0.91 | HIF1A (0.48) | HIF1APARP14PARP10MAOBSMN1; SMN2 | |
| SCHEMBL8621428 | 0.89 | MAPT (0.45) | HIF1APARP14PARP10MAOBL3MBTL1 | |
| SCHEMBL8623908 | 0.88 | HIF1A (0.46) | HIF1APARP14PARP10MAOBSMN1; SMN2 | |
| SCHEMBL8621226 | 0.86 | L3MBTL1 (0.46) | HIF1APARP14PARP10MAOBSMN1; SMN2 | |
| SCHEMBL8617222 | 0.84 | CDK4 (0.44) | MAOBL3MBTL1ALDH1A1MAPTKMT2A | |
| SCHEMBL8617286 | 0.84 | PTGDR2 (0.46) | SMN1; SMN2ALDH1A1MAPTHTTMEN1 | |
| SCHEMBL8620478 | 0.84 | MRGPRX4 (0.43) | HIF1ASMN1; SMN2L3MBTL1KDM4EMAPT | |
| SCHEMBL8617305 | 0.83 | ALDH1A1 (0.52) | HIF1APARP14PARP10MAOBSMN1; SMN2 | |
| SCHEMBL8622457 | 0.83 | L3MBTL1 (0.40) | HIF1AL3MBTL1KDM4EMAPTHPGD | |
| SCHEMBL8620420 | 0.83 | HIF1A (0.44) | HIF1APARP14PARP10SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0658541-B1 | PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO (JP) | 1998-05-20 | — | — | EP | disclosed |
| US-5510506-A | Process for producing carboxylic acid derivatives | SHIONOGI & CO., LTD. (JP) | 1996-04-23 | — | — | US | disclosed |
| EP-0658541-A1 | PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1995-06-21 | — | — | EP | disclosed |