Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | STS | P08842 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8613995 | 0.93 | TSHR (0.54) | ALDH1A1STSTSHRTDP1L3MBTL1 | |
| SCHEMBL8615797 | 0.90 | TSHR (0.55) | ALDH1A1STSTSHRTDP1L3MBTL1 | |
| SCHEMBL8613925 | 0.89 | TSHR (0.47) | ALDH1A1STSTSHRTDP1L3MBTL1 | |
| SCHEMBL5569165 | 0.81 | HSD11B1 (0.47) | ALDH1A1STSTSHRHSD11B1LMNA | |
| SCHEMBL12788120 | 0.80 | STS (0.47) | ALDH1A1STSTSHRL3MBTL1HSD11B1 | |
| SCHEMBL5738305 | 0.78 | HSD11B1 (0.43) | ALDH1A1STSTSHRHSD11B1HTR1D | |
| SCHEMBL11573891 | 0.76 | ALDH1A1 (0.53) | ALDH1A1STSTSHRTDP1L3MBTL1 | |
| SCHEMBL5565709 | 0.75 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1HSD11B1HTR1DHTR1A | |
| SCHEMBL7297972 | 0.74 | STS (0.44) | ALDH1A1STSTSHRTDP1L3MBTL1 | |
| SCHEMBL3181925 | 0.72 | KDM4E (0.49) | ALDH1A1TSHRL3MBTL1HSD11B1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537879-B1 | Aryl triflate compound, radiologically acid producing agent, radiologically acid producing agent system, and radiosensitive composition | HITACHI CHEMICAL CO LTD (JP) | 1998-04-29 | — | — | EP | disclosed |
| US-5302725-A | Aryl triflate compounds and radiologically acid producing agents thereof | HITACHI CHEMICAL CO., LTD. (JP) | 1994-04-12 | — | — | US | disclosed |
| EP-0537879-A1 | Aryl triflate compound, radiologically acid producing agent, radiologically acid producing agent system, and radiosensitive composition | HITACHI CHEMICAL CO., LTD. (JP) | 1993-04-21 | — | — | EP | disclosed |
| US-5198402-A | ARYL TRIFLATE COMPOUND, RADIOLOGICALLY ACID PRODUCING AGENT, RADIOLOGICALLY ACID PRODUCING AGENT SYSTEM, AND RADIOSENSITIVE COMPOSITION | HITACHI CHEMICAL COMPANY LTD. (JP) | 1993-03-30 | — | — | US | disclosed |