Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 4/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 4/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13793975 | 0.83 | L3MBTL1 (0.55) | ABCB1APPCA12CA1CA2 | |
| SCHEMBL1539372 | 0.81 | L3MBTL1 (0.53) | ABCB1HTR1AABCG2L3MBTL1ATM | |
| SCHEMBL1539377 | 0.81 | CDK4 (0.46) | HTR1AADRA1DADRA1AADRA1BRXRA | |
| SCHEMBL105847 | 0.80 | IDO1 (0.57) | CA12CA1CA2CA4CA7 | |
| SCHEMBL8622762 | 0.79 | HTR1A (0.51) | ABCB1HTR1AABCG2 | |
| SCHEMBL15049434 | 0.78 | IDO1 (0.55) | CA12CA1CA2CA4CA7 | |
| SCHEMBL467588 | 0.78 | IDO1 (0.55) | CA12CA1CA2CA4CA7 | |
| SCHEMBL483546 | 0.78 | MCL1 (0.61) | ABCB1APPHTR1AIDO1L3MBTL1 | |
| SCHEMBL9235134 | 0.78 | ABCB1 (0.50) | ABCB1APPCA12CA1CA2 | |
| SCHEMBL8591079 | 0.77 | ABCB1 (0.46) | ABCB1APPCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0658541-B1 | PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO (JP) | 1998-05-20 | — | — | EP | disclosed |
| US-5510506-A | Process for producing carboxylic acid derivatives | SHIONOGI & CO., LTD. (JP) | 1996-04-23 | — | — | US | disclosed |