Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.51 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 11/20 | 0.47 |
| ▸ | DRD2 | P14416 | 3/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1539372 | 0.86 | L3MBTL1 (0.53) | HTR1ANISCHABCB1DRD2ABCG2 | |
| SCHEMBL11746990 | 0.82 | HTR1A (0.49) | HTR1AADRA2AADRA2BADRA2CNISCH | |
| SCHEMBL1838476 | 0.79 | HTR1A (0.51) | HTR1AADRA2AADRA2BADRA2CNISCH | |
| SCHEMBL2289101 | 0.79 | ALDH1A1 (0.54) | HTR1AADRA2AADRA2BADRA2CNISCH | |
| SCHEMBL7568432 | 0.79 | PPARG (0.41) | HTR1AADRA2AADRA2BADRA2CNISCH | |
| SCHEMBL8593055 | 0.79 | HTR1A (0.48) | HTR1AADRA2AADRA2BADRA2CNISCH | |
| SCHEMBL1539377 | 0.79 | CDK4 (0.46) | HTR1ANISCH | |
| SCHEMBL8620530 | 0.79 | ABCB1 (0.50) | HTR1AABCB1ABCG2 | |
| SCHEMBL10784832 | 0.79 | HTR1A (0.73) | HTR1AADRA2AADRA2BADRA2CNISCH | |
| SCHEMBL4262567 | 0.77 | L3MBTL1 (0.60) | HTR1AADRA2AADRA2BADRA2CNISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0658541-B1 | PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO (JP) | 1998-05-20 | — | — | EP | disclosed |
| US-5510506-A | Process for producing carboxylic acid derivatives | SHIONOGI & CO., LTD. (JP) | 1996-04-23 | — | — | US | disclosed |
| EP-0658541-A1 | PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1995-06-21 | — | — | EP | disclosed |