Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 7/20 | 0.56 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | KMO | O15229 | 2/20 | 0.40 |
| ▸ | C1R | P00736 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | USP1 | O94782 | 1/20 | 0.37 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8616368 | 0.85 | ACP1 (0.41) | ACP1PDE10AMEN1KMT2AKDM4E | |
| SCHEMBL8613381 | 0.84 | ACP1 (0.46) | ACP1PDE10AC1RIGF1R | |
| SCHEMBL8613901 | 0.84 | ACP1 (0.51) | ACP1CYP1A2CYP2C19RECQLCYP3A4 | |
| SCHEMBL8616415 | 0.84 | ACP1 (0.42) | ACP1PDE10ACYP1A2CYP2C19CYP3A4 | |
| SCHEMBL8620892 | 0.83 | HTT (0.47) | ACP1CYP1A2CYP2C19CYP3A4MEN1 | |
| SCHEMBL8617806 | 0.83 | ACP1 (0.39) | ACP1PDE10AMEN1KMT2A | |
| SCHEMBL8618214 | 0.83 | ACP1 (0.53) | ACP1PDE10ATRPV1 | |
| SCHEMBL8616287 | 0.81 | PDE10A (0.49) | ACP1PDE10ATRPV1MEN1KMT2A | |
| SCHEMBL8617753 | 0.81 | ACP1 (0.51) | ACP1PDE10ACYP3A4MEN1KMT2A | |
| SCHEMBL8617537 | 0.81 | ACP1 (0.54) | ACP1PDE10ATRPV1KMODHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726254-B1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5627193-A | MEDICAL DIAGNOSIS, CARDIOVASCULAR DIAORDERS AND PROTECTION OF ORGANS FOR TRANSPLANTATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-06 | — | — | US | disclosed |
| EP-0726254-A1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-08-14 | — | — | EP | disclosed |