Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 6/20 | 0.46 |
| ▸ | IGF1R | P08069 | 5/20 | 0.41 |
| ▸ | C1R | P00736 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.39 |
| ▸ | ABL1 | P00519 | 3/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8614048 | 0.87 | ACP1 (0.42) | ACP1PDE10A | |
| SCHEMBL8617748 | 0.86 | ACP1 (0.52) | ACP1IGF1R | |
| SCHEMBL8620622 | 0.84 | ACP1 (0.56) | ACP1IGF1RC1RPDE10A | |
| SCHEMBL8614757 | 0.84 | PDE10A (0.44) | ACP1PDE10A | |
| SCHEMBL8615054 | 0.84 | PDE10A (0.55) | ACP1PDE10A | |
| SCHEMBL8616674 | 0.84 | ACP1 (0.54) | ACP1IGF1R | |
| SCHEMBL8618733 | 0.84 | LMNA (0.45) | ACP1PDE10AABL1 | |
| SCHEMBL8616443 | 0.83 | ACP1 (0.41) | ACP1PDE10A | |
| SCHEMBL8617796 | 0.82 | ACP1 (0.51) | ACP1IGF1R | |
| SCHEMBL8614063 | 0.82 | PDE10A (0.46) | ACP1PDE10AABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726254-B1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5627193-A | MEDICAL DIAGNOSIS, CARDIOVASCULAR DIAORDERS AND PROTECTION OF ORGANS FOR TRANSPLANTATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-06 | — | — | US | disclosed |
| EP-0726254-A1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-08-14 | — | — | EP | disclosed |