Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 7/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.34 |
| ▸ | TSPO | P30536 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8620753 | 1.00 | TRPV4 (0.35) | TRPV4CYP11B1CYP11B2FFAR1FFAR4 | |
| SCHEMBL8616906 | 0.92 | TRPV4 (0.36) | TRPV4CYP11B1CYP11B2FFAR1FFAR4 | |
| SCHEMBL8616904 | 0.92 | TRPV4 (0.36) | TRPV4CYP11B1CYP11B2FFAR1FFAR4 | |
| SCHEMBL8621546 | 0.92 | TNNC1 (0.33) | TRPV4CYP11B1CYP11B2FFAR1FFAR4 | |
| SCHEMBL8621544 | 0.92 | TNNC1 (0.33) | TRPV4CYP11B1CYP11B2FFAR1FFAR4 | |
| SCHEMBL8618031 | 0.91 | HAO1 (0.38) | FFAR1FFAR4HAO1GRM5 | |
| SCHEMBL8618028 | 0.91 | HAO1 (0.38) | FFAR1FFAR4HAO1GRM5 | |
| SCHEMBL8621577 | 0.90 | NFE2L2 (0.39) | FFAR1FFAR4TSPODRD3GRM5 | |
| SCHEMBL8621573 | 0.90 | NFE2L2 (0.39) | FFAR1FFAR4TSPODRD3GRM5 | |
| SCHEMBL8618584 | 0.86 | GRM5 (0.35) | FFAR1FFAR4GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648723-B1 | Diphenylacetylene compound, process for preparing the same and liquid crystal composition and element comprising the same | SUMITOMO CHEMICAL CO (JP) | 1998-05-20 | — | — | EP | disclosed |
| US-5658489-A | EXCELLENT ANISOTROPY OF REFRACTIVE INDEX; LOW VISCOSITY | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-08-19 | — | — | US | disclosed |
| EP-0648723-A1 | Diphenylacetylene compound, process for preparing the same and liquid crystal composition and element comprising the same | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1995-04-19 | — | — | EP | disclosed |