Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1399032 | 0.84 | MAPT (0.47) | MAPTHCAR2ALDH1A1PPARDTTR | |
| SCHEMBL687973 | 0.84 | MAPT (0.47) | MAPTHCAR2ALDH1A1PPARDTTR | |
| SCHEMBL8115684 | 0.83 | MAPT (0.50) | MAPTHCAR2ALDH1A1TTRDPP4 | |
| SCHEMBL8123279 | 0.83 | MAPT (0.50) | MAPTHCAR2ALDH1A1TTRDPP4 | |
| SCHEMBL15163745 | 0.82 | MAPT (0.46) | MAPTHCAR2ALDH1A1TTRDPP4 | |
| SCHEMBL12784109 | 0.79 | MAPT (0.50) | MAPTHCAR2ALDH1A1TTRDPP4 | |
| SCHEMBL17398721 | 0.77 | MAPT (0.42) | MAPTHCAR2ALDH1A1PPARDTTR | |
| SCHEMBL13502893 | 0.76 | MAPT (0.47) | MAPTHCAR2ALDH1A1TTRDPP4 | |
| Butyric Acid SCHEMBL11237541 | 0.74 | HCAR2 (0.42) | MAPTHCAR2ALDH1A1PPARDTTR | |
| SCHEMBL12315645 | 0.73 | PPARD (0.47) | MAPTPPARDFNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080085273-A1 | VEHICLE FOR THE TRANSPORT OF A CHOSEN MOLECULE TO A CELL | SYNVOLUX IP B.V. (NL) | 2008-04-10 | — | — | US | disclosed |
| EP-0842197-A2 | BROAD SPECIFICITY ANTIBODIES | THE MINISTER OF AGRICULTURE FISHERIES AND FOOD IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN (GB) | 1998-05-20 | — | — | EP | disclosed |
| WO-1997005170-A2 | BROAD SPECIFICITY ANTIBODIES | THE MINISTER OF AGRICULTURE FISHERIES & FOOD IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1997-02-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080085273-A1 | VEHICLE FOR THE TRANSPORT OF A CHOSEN MOLECULE TO A CELL | EPCAM, CD44, SELE | MAPT 3106/4885HCAR2 1118/4885ALDH1A1 2664/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.