Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8115684 | 0.84 | MAPT (0.50) | MAPTHCAR2ALDH1A1TTRDPP4 | |
| SCHEMBL8123279 | 0.84 | MAPT (0.50) | MAPTHCAR2ALDH1A1TTRDPP4 | |
| SCHEMBL15163745 | 0.83 | MAPT (0.46) | MAPTHCAR2ALDH1A1TTRDPP4 | |
| SCHEMBL13502893 | 0.81 | MAPT (0.47) | MAPTHCAR2ALDH1A1TTRDPP4 | |
| SCHEMBL1399032 | 0.81 | MAPT (0.47) | MAPTHCAR2ALDH1A1TTRDPP4 | |
| SCHEMBL687973 | 0.81 | MAPT (0.47) | MAPTHCAR2ALDH1A1TTRDPP4 | |
| SCHEMBL8620959 | 0.79 | MAPT (0.46) | MAPTHCAR2ALDH1A1TTRDPP4 | |
| SCHEMBL14681171 | 0.79 | HCAR2 (0.50) | MAPTHCAR2ALDH1A1TTRCA12 | |
| SCHEMBL94678 | 0.76 | — | — | |
| SCHEMBL264771 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8324427-B2 | Substances analogous to MK8383 and agricultural and horticultural disease control agents | MEIJI SEIKA KAISHA, LTD. (JP) | 2012-12-04 | — | — | US | disclosed |
| US-20110065792-A1 | NOVEL SUBSTANCES ANALOGOUS TO MK8383 AND AGRICULTURAL AND HORTICULTURAL DISEASE CONTROL AGENTS | MEIJI SEIKA KAISHA, LTD. (JP) | 2011-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110065792-A1 | NOVEL SUBSTANCES ANALOGOUS TO MK8383 AND AGRICULTURAL AND HORTICULTURAL DISEASE CONTROL AGENTS | TSG101, PPME1, DDT | MAPT 1289/4885HCAR2 3001/4885ALDH1A1 3586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.