Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 8/20 | 0.50 |
| ▸ | CA12 | O43570 | 7/20 | 0.50 |
| ▸ | CA2 | P00918 | 7/20 | 0.50 |
| ▸ | CA1 | P00915 | 6/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | OGA | O60502 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9351909 | 1.00 | CA9 (0.50) | CA9CA12CA2CA1TSHR | |
| SCHEMBL22677480 | 1.00 | CA9 (0.50) | CA9CA12CA2CA1TSHR | |
| SCHEMBL22677465 | 1.00 | CA9 (0.50) | CA9CA12CA2CA1TSHR | |
| SCHEMBL8434120 | 1.00 | CA9 (0.50) | CA9CA12CA2CA1TSHR | |
| SCHEMBL2614790 | 0.86 | CA9 (0.45) | CA9CA12CA2CA1TSHR | |
| SCHEMBL30236727 | 0.86 | CA9 (0.45) | CA9CA12CA2CA1TSHR | |
| SCHEMBL24024779 | 0.85 | CA9 (0.58) | CA9CA12CA2CA1TSHR | |
| SCHEMBL22677696 | 0.85 | CA9 (0.58) | CA9CA12CA2CA1TSHR | |
| SCHEMBL22677780 | 0.85 | CA9 (0.58) | CA9CA12CA2CA1TSHR | |
| SCHEMBL19806807 | 0.85 | CA9 (0.58) | CA9CA12CA2CA1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5777136-A | Process for the glycosidation of colchicine derivatives and the products obtained thereby | INDENA S.P.A. (IT) | 1998-07-07 | — | — | US | claimed |
| JP-9309896-A | — | — | None | — | — | JP | disclosed |
| US-20230321130-A1 | Senolytic Compositions and Uses Thereof | Rubedo Life Sciences, Inc. | 2023-10-12 | — | — | US | disclosed |
| US-11026963-B2 | Senolytic compositions and uses thereof | Rubedo Life Sciences, Inc. (US) | 2021-06-08 | — | — | US | disclosed |
| US-20200016185-A1 | SENOLYTIC COMPOSITIONS AND USES THEREOF | Rubedo Life Sciences, Inc. | 2020-01-16 | — | — | US | disclosed |
| JP-H09309896-A | GLYCOSIDATION OF COLCHICINE DERIVATIVE AND ITS FORMED PRODUCT | INDENA SPA | 1997-12-02 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11026963-B2 | Senolytic compositions and uses thereof | SENP3, SENP6, SENP1 | CA9 2559/4885CA12 3221/4885CA2 4461/4885 |
| US-20200016185-A1 | SENOLYTIC COMPOSITIONS AND USES THEREOF | SENP3, SENP6, SENP1 | CA9 2559/4885CA12 3221/4885CA2 4461/4885 |
| US-20230321130-A1 | Senolytic Compositions and Uses Thereof | SENP3, SENP6, SENP1 | CA9 2559/4885CA12 3221/4885CA2 4461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.