Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL666917 | 0.83 | TSHR (0.40) | TSHRALDH1A1 | |
| SCHEMBL2799572 | 0.81 | TSHR (0.34) | TSHR | |
| Ammonia Solution, Strong SCHEMBL27777444 | 0.79 | CTSK (0.32) | — | |
| SCHEMBL876357 | 0.79 | — | — | |
| SCHEMBL6014318 | 0.79 | TSHR (0.33) | TSHR | |
| SCHEMBL6612206 | 0.79 | TSHR (0.33) | TSHR | |
| SCHEMBL28390679 | 0.79 | TSHR (0.39) | TSHR | |
| SCHEMBL1923846 | 0.78 | ALDH1A1 (0.37) | TSHRALDH1A1TDP1HSD17B10FFAR3 | |
| SCHEMBL28988598 | 0.78 | — | — | |
| SCHEMBL16659456 | 0.78 | TSHR (0.32) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5709715-A | Silicon or silica substrate with a modified surface, process for producing the same, new orthoesters and process for producing the same | OWENS-CORNING FIBERGLAS TECHNOLOGY INC. (US) | 1998-01-20 | — | — | US | claimed |
| US-5709715-A | Silicon or silica substrate with a modified surface, process for producing the same, new orthoesters and process for producing the same | OWENS-CORNING FIBERGLAS TECHNOLOGY INC. (US) | 1998-01-20 | — | — | US | disclosed |