Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.49 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24845122 | 0.81 | RAB9A (0.53) | SMN1; SMN2CYP1A2ALDH1A1RAB9AMAPT | |
| SCHEMBL8623249 | 0.80 | RAB9A (0.52) | SMN1; SMN2CYP1A2ALDH1A1RAB9AMAPT | |
| SCHEMBL28261177 | 0.80 | ALDH1A1 (0.55) | PTGS2SMN1; SMN2ALDH1A1RAB9AMAPT | |
| SCHEMBL24845608 | 0.80 | RAB9A (0.52) | SMN1; SMN2CYP1A2ALDH1A1RAB9AMAPT | |
| SCHEMBL6655190 | 0.80 | ALDH1A1 (0.68) | KMT2ASMN1; SMN2ALDH1A1RAB9ALMNA | |
| SCHEMBL3285385 | 0.79 | CYP1A2 (0.51) | KMT2ASMN1; SMN2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1560458 | 0.79 | CYP1A2 (0.51) | KMT2ASMN1; SMN2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11649715 | 0.78 | ALDH1A1 (0.69) | KMT2ASMN1; SMN2CYP1A2ALDH1A1RAB9A | |
| SCHEMBL2803614 | 0.77 | CYP1A2 (0.49) | KMT2ASMN1; SMN2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL13757728 | 0.77 | SMN1; SMN2 (0.55) | KMT2ASMN1; SMN2CYP1A2ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817677-A | ANTITHROMBOSIS AGENTS | DR. KARL THOMAE GMBH (DE) | 1998-10-06 | — | — | US | disclosed |