Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.43 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.43 |
| ▸ | STS | P08842 | 3/20 | 0.43 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24845122 | 0.86 | RAB9A (0.53) | RAB9AMAPTSMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL28261177 | 0.85 | ALDH1A1 (0.55) | RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL24845608 | 0.85 | RAB9A (0.52) | RAB9AMAPTSMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL6655190 | 0.84 | ALDH1A1 (0.68) | RAB9AMAPTSMN1; SMN2ALDH1A1CYP19A1 | |
| SCHEMBL11649715 | 0.83 | ALDH1A1 (0.69) | RAB9AMAPTSMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL13757728 | 0.81 | SMN1; SMN2 (0.55) | RAB9AMAPTSMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL6774389 | 0.81 | RAB9A (0.49) | RAB9AMAPTSMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL8621723 | 0.80 | PTGS2 (0.52) | RAB9AMAPTSMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL26834384 | 0.80 | ALDH1A1 (0.55) | RAB9AMAPTSMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL13012721 | 0.79 | ALDH1A1 (0.54) | RAB9AMAPTSMN1; SMN2ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817677-A | ANTITHROMBOSIS AGENTS | DR. KARL THOMAE GMBH (DE) | 1998-10-06 | — | — | US | disclosed |