Benzotriazole

Benzotriazole

SCHEMBL8621732

Nc1ccc(O)cc1.c1ccc2[nH]nnc2c1

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.45
HSD17B10 Q99714 2/20 0.45
CA3 P07451 1/20 0.45
CYP3A4 P08684 1/20 0.45
THRB P10828 1/20 0.45
ALOX15 P16050 1/20 0.45
CA6 P23280 1/20 0.45
CASP1 P29466 1/20 0.45
HIF1A Q16665 1/20 0.45
CA14 Q9ULX7 1/20 0.45
MAPT P10636 4/20 0.40
NPC1 O15118 4/20 0.40
RAB9A P51151 3/20 0.40
GFER P55789 2/20 0.40
POLB P06746 2/20 0.40
KDM4E B2RXH2 2/20 0.40
TP53 P04637 1/20 0.40
HPGD P15428 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
FGFR1 P11362 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzotriazole SCHEMBL3831032 0.85 TDP1 (0.44) ALDH1A1HSD17B10CA3CA14MAPT
Benzotriazole SCHEMBL5429172 0.85 TDP1 (0.44) ALDH1A1HSD17B10CA3CA14MAPT
Benzotriazole SCHEMBL28857770 0.85 TDP1 (0.44) ALDH1A1HSD17B10CA3CA14MAPT
Benzotriazole SCHEMBL1265047 0.85 TDP1 (0.44) ALDH1A1HSD17B10CA3CA14MAPT
Benzotriazole SCHEMBL27770572 0.85 TSHR (0.44) ALDH1A1HSD17B10CYP3A4CASP1MAPT
Benzotriazole SCHEMBL28307501 0.84 TDP1 (0.42) ALDH1A1HSD17B10CA3CA14MAPT
Benzotriazole SCHEMBL4734294 0.83 ALDH1A1 (0.39) ALDH1A1HSD17B10CYP3A4MAPTNPC1
Benzotriazole SCHEMBL14975745 0.83 ACHE (0.45) ALDH1A1HSD17B10CYP3A4ALOX15MAPT
Benzotriazole SCHEMBL28212495 0.81 NPC1 (0.38) ALDH1A1HSD17B10NPC1RAB9APOLB
Benzotriazole SCHEMBL6088869 0.81 ALDH1A1 (0.41) ALDH1A1HSD17B10CYP3A4MAPTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2811010-B1 VEHICLE-GLASS CLEANING FLUID COMPOSITION COMPRISING ANIONIC SURFACTANT AND TARTARIC ACID KUKDONG JEYEN CO LTD (KR) 2017-04-05 EP claimed
EP-2178991-B1 STABILIZING AQUEOUS ANIONIC RESINOUS DISPERSIONS WITH CHELATING AGENTS PPG IND OHIO INC (US) 2016-03-16 EP claimed
EP-2178942-B1 ELECTRODEPOSITION COATINGS FOR USE OVER ALUMINUM SUBSTRATES PPG IND OHIO INC (US) 2013-05-29 EP claimed
EP-0566902-B1 Method of monitoring and controlling corrosion inhibitor dosage in aqueous systems NALCO CHEMICAL CO (US) 1998-05-13 EP claimed
EP-0375385-B1 Scale control GRACE W R & CO (US) 1993-11-10 EP claimed
EP-0155846-B1 A METHOD OF INHIBITING CORROSION IN AQUEOUS SYSTEMS W.R. Grace & Co.-Conn. (US) 1992-07-15 EP claimed