SCHEMBL9469211

SCHEMBL9469211

C=Cc1ccc(COc2ccc(C=O)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.59
ALDH1A1 P00352 3/20 0.51
SMN1; SMN2 Q16637 3/20 0.51
LMNA P02545 1/20 0.51
MAPT P10636 1/20 0.51
HPGD P15428 1/20 0.51
NPC1 O15118 2/20 0.49
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
KDM4E B2RXH2 2/20 0.49
MAOA P21397 4/20 0.46
MAOB P27338 4/20 0.46
APP P05067 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.44
PTPN2 P17706 1/20 0.44
PTPN1 P18031 1/20 0.44
PTPN11 Q06124 1/20 0.44
CASP3 P42574 1/20 0.44
SENP8 Q96LD8 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8621941 1.00 RAB9A (0.59) RAB9AALDH1A1SMN1; SMN2LMNAMAPT
SCHEMBL6388039 0.91 APP (0.54) RAB9AALDH1A1SMN1; SMN2NPC1MAOB
SCHEMBL11614936 0.91 RAB9A (0.69) RAB9AALDH1A1SMN1; SMN2LMNAMAPT
SCHEMBL23223734 0.91 RAB9A (0.69) RAB9AALDH1A1SMN1; SMN2LMNAMAPT
SCHEMBL13242652 0.91 APP (0.54) RAB9AALDH1A1SMN1; SMN2NPC1MAOB
SCHEMBL31453872 0.85 APP (0.48) RAB9AALDH1A1SMN1; SMN2HPGDNPC1
SCHEMBL8589028 0.84 RAB9A (0.61) RAB9AALDH1A1SMN1; SMN2LMNAMAPT
SCHEMBL2849932 0.84 APP (0.59) RAB9AALDH1A1SMN1; SMN2LMNAMAPT
SCHEMBL865349 0.84 RAB9A (0.71) RAB9AALDH1A1SMN1; SMN2LMNAMAPT
SCHEMBL21906201 0.82 MAOA (0.72) RAB9AALDH1A1NPC1TDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103435748-B A kind of Zn recycled in pure water medium 2+the preparation method of probe and application GUANGZHOU CHEMISTRY CO., LTD. CHINESE ACADEMY OF SCIENCES (CN) 2016-01-20 CN claimed
CN-103374100-B Preparation and application of europium base polymer with long fluorescence lifetime and capable of selective recognition of anion CAS GUANGZHOU CHEMISTRY CO LTD 2015-06-10 CN claimed
CN-103374132-B Preparation and application of metal ion directly induced fluorescent supramolecular gel CAS GUANGZHOU CHEMISTRY CO LTD 2015-04-08 CN claimed
CN-117843840-A Porphyrin-based covalent organic polymer and preparation method and application thereof 西安石油大学 2024-04-09 CN disclosed
EP-3337835-B1 COMPOSITION OF CROSS-LINKED POLYMERS COMPRISING PENDING EXCHANGEABLE BONDS AND EXCHANGEABLE CROSS-LINKS, VIA ALDEHYDE-IMINE AND/OR IMINE-IMINE EXCHANGE REACTIONS, PREPARATION PROCESSES AND USE ECOLE SUPERIEURE PHYSIQUE & CHIMIE IND VILLE DE PARIS (FR) 2021-12-01 EP disclosed
US-10889715-B2 Polymer composition comprising crosslinked silicones with exchangeable crosslinking points, preparation method and uses ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (FR) 2021-01-12 US disclosed
EP-3337832-B1 COMPOSITION COMPRISING A CROSS-LINKED POLYMER NETWORK COMPRISING PENDING LINKS AND CROSS-LINKS EXCHANGEABLE BY ALDEHYDE-IMINE AND/OR BY IMINE-IMINE EXCHANGE REACTIONS, PREPARATION PROCESS AND USE ECOLE SUPERIEURE PHYSIQUE & CHIMIE IND VILLE DE PARIS (FR) 2019-07-17 EP disclosed
US-20190127583-A1 POLYMER COMPOSITION COMPRISING CROSSLINKED SILICONES WITH EXCHANGEABLE CROSSLINKING POINTS, PREPARATION METHOD AND USES ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRI ELLES DE LA VILLE DE PARIS (FR) 2019-05-02 US disclosed
US-9994651-B2 Composition of cross-linked polymers comprising pending exchangeable bonds and exchangeable cross-links, via aldehyde-imine and/or imine-imine exchange reactions, preparation processes and use ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (FR) 2018-06-12 US disclosed
US-9994651-B2 Composition of cross-linked polymers comprising pending exchangeable bonds and exchangeable cross-links, via aldehyde-imine and/or imine-imine exchange reactions, preparation processes and use ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (FR) 2018-06-12 US disclosed
CN-107602478-A A kind of novel benzimidazoles ion monomer and preparation method thereof 浙江大学 2018-01-19 CN disclosed
WO-2017029311-A1 COMPOSITION OF CROSS-LINKED POLYMERS COMPRISING PENDING EXCHANGEABLE BONDS AND EXCHANGEABLE CROSS-LINKS, VIA ALDEHYDE-IMINE AND/OR IMINE-IMINE EXCHANGE REACTIONS, PREPARATION PROCESSES AND USE ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (FR) 2017-02-23 WO disclosed
US-20170051082-A1 COMPOSITION OF CROSS-LINKED POLYMERS COMPRISING PENDING EXCHANGEABLE BONDS AND EXCHANGEABLE CROSS-LINKS, VIA ALDEHYDE-IMINE AND/OR IMINE-IMINE EXCHANGE REACTIONS, PREPARATION PROCESSES AND USE ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (FR) 2017-02-23 US disclosed
CN-103435748-B A kind of Zn recycled in pure water medium 2+the preparation method of probe and application GUANGZHOU CHEMISTRY CO., LTD. CHINESE ACADEMY OF SCIENCES (CN) 2016-01-20 CN disclosed
CN-103374100-B Preparation and application of europium base polymer with long fluorescence lifetime and capable of selective recognition of anion CAS GUANGZHOU CHEMISTRY CO LTD 2015-06-10 CN disclosed
CN-103374132-B Preparation and application of metal ion directly induced fluorescent supramolecular gel CAS GUANGZHOU CHEMISTRY CO LTD 2015-04-08 CN disclosed
CN-101434677-B White fluorescent polymeric compounds, and preparation and use thereof UNIV SUZHOU 2011-04-06 CN disclosed
CN-101434677-A White fluorescent polymeric compounds, and preparation and use thereof UNIV SOOCHOW (CN) 2009-05-20 CN disclosed
US-5219710-A Optical waveguides; change refractive index upon exposure to actinic radiation; heat resistant ALLIED-SIGNAL INC. (US) 1993-06-15 US disclosed
WO-1993011169-A1 POLYMERIC NITRONES HAVING A STYRENE-DERIVED BACKBONE CHAIN ALLIED-SIGNAL INC. (US) 1993-06-10 WO disclosed