SCHEMBL8622225

SCHEMBL8622225

CCC(Oc1ccc(C(C)(C)CC)cc1C(C)(C)CC)C(=O)Nc1c[c]c(Cl)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 6/20 0.41
MEN1 O00255 5/20 0.41
KMT2A Q03164 5/20 0.41
MAPK1 P28482 5/20 0.41
SMN1; SMN2 Q16637 4/20 0.41
ALDH1A1 P00352 2/20 0.41
ACACB O00763 1/20 0.38
APOBEC3A P31941 1/20 0.36
APOBEC3G Q9HC16 1/20 0.36
MAPT P10636 6/20 0.35
HTT P42858 3/20 0.35
UBE2N P61088 2/20 0.35
GLA P06280 1/20 0.35
MITF O75030 1/20 0.35
LMNA P02545 2/20 0.34
GAA P10253 2/20 0.34
KLK7 P49862 3/20 0.32
RAD52 P43351 2/20 0.32
STAT3 P40763 1/20 0.32
RCE1 Q9Y256 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11002253 0.87 NPSR1 (0.43) NPSR1MEN1KMT2AMAPK1SMN1; SMN2
SCHEMBL7040054 0.84 NPSR1 (0.46) NPSR1MEN1KMT2AMAPK1SMN1; SMN2
SCHEMBL9868418 0.84 NPSR1 (0.48) NPSR1MEN1KMT2AMAPK1SMN1; SMN2
SCHEMBL8622770 0.83 NPSR1 (0.42) NPSR1MEN1KMT2AMAPK1SMN1; SMN2
SCHEMBL7767160 0.83 NPSR1 (0.45) NPSR1MEN1KMT2AMAPK1SMN1; SMN2
SCHEMBL11772726 0.83 SMN1; SMN2 (0.45) NPSR1MEN1KMT2AMAPK1SMN1; SMN2
SCHEMBL6161330 0.83 NPC1 (0.43) NPSR1MEN1KMT2AMAPK1SMN1; SMN2
SCHEMBL7044353 0.83 MEN1 (0.41) NPSR1MEN1KMT2AMAPK1SMN1; SMN2
SCHEMBL14564633 0.83 KMT2A (0.46) NPSR1MEN1KMT2AMAPK1SMN1; SMN2
SCHEMBL9848197 0.82 SMN1; SMN2 (0.44) NPSR1MEN1KMT2AMAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0464612-B1 Silver halide photographic materials FUJI PHOTO FILM CO LTD (JP) 1998-05-13 EP disclosed
EP-0456181-B1 Silver halide color photographic material and method for processing the same FUJI PHOTO FILM CO LTD (JP) 1996-08-14 EP disclosed
US-5529894-A PYRAZOLOAZOLE BASED MAGENTA COUPLER, TIMING COUPLER; SHARPNESS, DESILVERING PROPERTIES FUJI PHOTO FILM CO., LTD. (JP) 1996-06-25 US disclosed
EP-0326160-B1 Silver halide photographic material FUJI PHOTO FILM CO LTD (JP) 1995-12-27 EP disclosed
US-5459022-A Having improved color reproducibility, rapid processability FUJI PHOTO FILM CO., LTD. (JP) 1995-10-17 US disclosed
EP-0438150-B1 Silver halide colour photographic material FUJI PHOTO FILM CO LTD (JP) 1995-04-26 EP disclosed
EP-0310125-B1 Silver halide color photographic material FUJI PHOTO FILM CO LTD (JP) 1995-04-19 EP disclosed
EP-0438129-B1 Silver halide color photographic material FUJI PHOTO FILM CO LTD (JP) 1995-04-12 EP disclosed
EP-0287073-B1 Method for processing a silver halide photographic material FUJI PHOTO FILM CO LTD (JP) 1995-03-08 EP disclosed
EP-0423727-B1 Silver halide color photographic material containing colored coupler FUJI PHOTO FILM CO LTD (JP) 1995-01-11 EP disclosed
US-RE29379-E FUSED-RING DIAZOLE OR TRIAZOLE CONTAINING COUPLER FUJI PHOTO FILM CO., LTD. (JA) 1977-08-30 US disclosed
US-4021238-A SILVER HALIDE EMULSION LAYERS, DYES FUJI PHOTO FILM CO., LTD. (JA) 1977-05-03 US disclosed
US-4021248-A SILVER HALIDE FUJI PHOTO FILM CO., LTD. (JA) 1977-05-03 US disclosed
US-4015988-A SILVER HALIDE EMULSION, DYE COUPLERS FUJI PHOTO FILM CO., LTD. (JA) 1977-04-05 US disclosed
US-3990899-A DEVELOPING, UNCOLORED COUPLERS FUJI PHOTO FILM CO., LTD. (JA) 1976-11-09 US disclosed
US-3963499-A Photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JA) 1976-06-15 US disclosed
US-3948663-A Multi-layer color photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JA) 1976-04-06 US disclosed
US-3936303-A Photographic photosensitive element and developing method thereof FUJI PHOTO FILM CO., LTD. (JA) 1976-02-03 US disclosed
US-3933500-A Color photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JA) 1976-01-20 US disclosed
US-3930863-A MULTILAYER, HYDROQUINONE DERIVATIVES FUJI PHOTO FILM CO., LTD. (JA) 1976-01-06 US disclosed