Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 11/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | FPR1 | P21462 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8621615 | 0.81 | CCKBR (0.61) | CCKBRMEN1KMT2A | |
| SCHEMBL4424441 | 0.80 | GAA (0.46) | MEN1KMT2AHPGDSLC6A2 | |
| SCHEMBL8615202 | 0.79 | CCKBR (0.61) | CCKBRMEN1KMT2A | |
| Dimethylamine SCHEMBL8639336 | 0.73 | CCKBR (0.94) | CCKBR | |
| SCHEMBL4416338 | 0.71 | GABRP (0.46) | CCKBRMEN1KMT2AHPGDSLC6A2 | |
| SCHEMBL8621950 | 0.71 | CCKBR (0.61) | CCKBREPHX2 | |
| SCHEMBL8615476 | 0.71 | CCKBR (0.46) | CCKBRMEN1KMT2A | |
| SCHEMBL8639332 | 0.69 | CCKBR (0.73) | CCKBR | |
| SCHEMBL8638391 | 0.69 | CCKBR (0.64) | CCKBR | |
| SCHEMBL9014101 | 0.68 | CCKBR (0.50) | CCKBREPHX2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0558104-B1 | 1,5-Benzodiazepine derivatives and their use in medicine | GLAXO WELLCOME SPA (IT) | 1998-07-29 | — | — | EP | disclosed |
| EP-0623118-B1 | CARBAMATE DERIVATIVES AND THEIR USE IN MEDICINE | GLAXO WELLCOME SPA (IT) | 1998-05-13 | — | — | EP | disclosed |
| US-5637697-A | ANTAGONIST TO GASTRIN AND(OR) CHLOROCYSTOKININ | GLAXO SPA (IT) | 1997-06-10 | — | — | US | disclosed |
| US-5580895-A | GASTROINTESTINAL OR CENTRAL NERVOUS SYSTEM DISORDERS | GLAXO SPA (IT) | 1996-12-03 | — | — | US | disclosed |
| US-5486514-A | GASTRIN, CHOLECYSTOKININ RECEPTOR ANTAGONISTS | GLAXO SPA (IT) | 1996-01-23 | — | — | US | disclosed |
| EP-0558104-A1 | 1,5-Benzodiazepine derivatives and their use in medicine | GLAXO S.p.A. (IT) | 1993-09-01 | — | — | EP | disclosed |