Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 7/20 | 0.35 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8625457 | 0.75 | AKR1C3 (0.40) | FDPSGGPS1PPARGPPARAAKR1C3 | |
| SCHEMBL8622492 | 0.73 | FDFT1 (0.40) | — | |
| SCHEMBL8624786 | 0.71 | FDPS (0.37) | FDPSGGPS1 | |
| SCHEMBL8624703 | 0.71 | FDPS (0.38) | FDPSGGPS1HPGD | |
| SCHEMBL8625448 | 0.70 | KDM4E (0.40) | FDPSGGPS1ALDH1A1KDM4EAKR1C3 | |
| SCHEMBL8621533 | 0.69 | FDPS (0.37) | FDPSGGPS1PKM | |
| SCHEMBL8947053 | 0.69 | FDFT1 (0.48) | — | |
| SCHEMBL14198058 | 0.65 | MAOB (0.65) | ALDH1A1KDM4EPKMHPGDMAPK1 | |
| SCHEMBL8620663 | 0.65 | FDFT1 (0.51) | — | |
| SCHEMBL9631998 | 0.63 | S1PR1 (0.37) | FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712396-A | PHOSPHONOSULFONATE COMPOUNDS USED FOR INHIBITING CHOLESTEROL BIOSYNTHESIS AND ATHEROSCLEROSIS | MAGNIN DAVID R (US) | 1998-01-27 | — | — | US | claimed |
| US-5712396-A | PHOSPHONOSULFONATE COMPOUNDS USED FOR INHIBITING CHOLESTEROL BIOSYNTHESIS AND ATHEROSCLEROSIS | MAGNIN DAVID R (US) | 1998-01-27 | — | — | US | disclosed |