Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 7/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.37 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.37 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PTPRB | P23467 | 1/20 | 0.36 |
| ▸ | PTPRG | P23470 | 1/20 | 0.36 |
| ▸ | ACP1 | P24666 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8621533 | 0.87 | FDPS (0.37) | FDPSPTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL8624786 | 0.85 | FDPS (0.37) | FDPSPTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL8625457 | 0.84 | AKR1C3 (0.40) | FDPSGGPS1 | |
| SCHEMBL8625448 | 0.84 | KDM4E (0.40) | FDPSPTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL8624700 | 0.71 | FDFT1 (0.38) | HPGD | |
| SCHEMBL8622493 | 0.71 | FDPS (0.35) | FDPSGGPS1HPGD | |
| SCHEMBL10252335 | 0.66 | HTR1A (0.69) | PTGER1PTGER4PTGER3PTGER2ABCB1 | |
| SCHEMBL2091568 | 0.65 | SLC6A3 (0.49) | SIGMAR1 | |
| SCHEMBL24041895 | 0.65 | HTR1A (0.46) | PTGER1PTGER4PTGER3PTGER2ABCB1 | |
| SCHEMBL8947210 | 0.65 | CETP (0.51) | FDPSGGPS1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712396-A | PHOSPHONOSULFONATE COMPOUNDS USED FOR INHIBITING CHOLESTEROL BIOSYNTHESIS AND ATHEROSCLEROSIS | MAGNIN DAVID R (US) | 1998-01-27 | — | — | US | claimed |
| US-5712396-A | PHOSPHONOSULFONATE COMPOUNDS USED FOR INHIBITING CHOLESTEROL BIOSYNTHESIS AND ATHEROSCLEROSIS | MAGNIN DAVID R (US) | 1998-01-27 | — | — | US | disclosed |