Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | FDPS | P14324 | 7/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.34 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8625457 | 0.88 | AKR1C3 (0.40) | FDPSAKR1C3AKR1C2GGPS1 | |
| SCHEMBL8624703 | 0.84 | FDPS (0.38) | FDPSPTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL8621533 | 0.82 | FDPS (0.37) | FDPSADRB2PTGER1PTGER4PTGER3 | |
| SCHEMBL8625443 | 0.72 | KDM4E (0.38) | KDM4EAKR1C3AKR1C2ADRB2 | |
| SCHEMBL8622493 | 0.70 | FDPS (0.35) | KDM4EFDPSAKR1C3ALDH1A1GGPS1 | |
| Phosphoric Acid SCHEMBL23302571 | 0.68 | ICAM1 (0.46) | KDM4EALDH1A1ADRB2 | |
| Sulfuric Acid SCHEMBL6263795 | 0.68 | ICAM1 (0.46) | KDM4EALDH1A1ADRB2 | |
| SCHEMBL9545863 | 0.67 | KDM4E (0.40) | KDM4EALDH1A1ADRB2 | |
| Sulfuric Acid SCHEMBL21225308 | 0.67 | ICAM1 (0.45) | KDM4EALDH1A1ADRB2 | |
| Sulfuric Acid SCHEMBL1678480 | 0.66 | ICAM1 (0.47) | KDM4EALDH1A1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712396-A | PHOSPHONOSULFONATE COMPOUNDS USED FOR INHIBITING CHOLESTEROL BIOSYNTHESIS AND ATHEROSCLEROSIS | MAGNIN DAVID R (US) | 1998-01-27 | — | — | US | claimed |
| US-5712396-A | PHOSPHONOSULFONATE COMPOUNDS USED FOR INHIBITING CHOLESTEROL BIOSYNTHESIS AND ATHEROSCLEROSIS | MAGNIN DAVID R (US) | 1998-01-27 | — | — | US | disclosed |