Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ESR1 | P03372 | 4/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.42 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10975295 | 0.85 | PRKCD (0.44) | ESR1ESR2MAPK1LTB4RSIGMAR1 | |
| SCHEMBL9320616 | 0.80 | SIGMAR1 (0.53) | ALDH1A1CYP3A4CYP1A2HSD17B10MAPK1 | |
| SCHEMBL5010076 | 0.78 | ALDH1A1 (0.51) | ALDH1A1KMT2ACYP3A4MAPTHSD17B10 | |
| SCHEMBL8616881 | 0.77 | LTB4R (0.55) | ALDH1A1KMT2AESR1ESR2CYP3A4 | |
| SCHEMBL4353469 | 0.77 | LTB4R (0.55) | ALDH1A1KMT2AESR1ESR2CYP3A4 | |
| SCHEMBL8621730 | 0.77 | LTB4R (0.55) | ALDH1A1KMT2AESR1ESR2CYP3A4 | |
| SCHEMBL10975102 | 0.76 | ESR1 (0.46) | ALDH1A1KMT2AESR1ESR2CYP3A4 | |
| SCHEMBL8618775 | 0.74 | MAPT (0.54) | ALDH1A1KDM4EMAPTHSD17B10SMN1; SMN2 | |
| SCHEMBL17942909 | 0.73 | LTB4R (0.49) | ALDH1A1KMT2AESR1ESR2CYP3A4 | |
| SCHEMBL8622548 | 0.73 | TSHR (0.54) | ALDH1A1KMT2AESR1ESR2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0659582-B1 | Reversible thermochromic composition | PILOT INK CO LTD (JP) | 1998-05-13 | — | — | EP | disclosed |
| US-5558700-A | QUINAZOLENE OR PYRIDINE ELECTRON DONOR, ELECTRON ACCEPTOR | THE PILOT INK CO., LTD. (JP) | 1996-09-24 | — | — | US | disclosed |
| EP-0659582-A1 | Reversible thermochromic composition | THE PILOT INK CO., LTD. (JP) | 1995-06-28 | — | — | EP | disclosed |
| EP-0061128-B1 | PYRIDINE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND SYSTEMS CONTAINING THEM | STERLING DRUG INC. (US) | 1985-09-04 | — | — | EP | disclosed |
| US-4446321-A | COLOR FORMERS, CARBON-FREE DUPLICATION | STERLING DRUG INC. (US) | 1984-05-01 | — | — | US | disclosed |
| US-4363503-A | FOR PRESSURE SENSITIVE CARBONLESS DUPLICATING AND THERMAL MARKING SYSTEMS | STERLING DRUG INC. (US) | 1982-12-14 | — | — | US | disclosed |
| EP-0061128-A1 | Pyridine compounds, process for their preparation and systems containing them | STERLING DRUG INC. (US) | 1982-09-29 | — | — | EP | disclosed |