SCHEMBL8622565

SCHEMBL8622565

CCO/N=C1/CCS(=O)(=O)c2ccc(C(=O)c3cnn(CC)c3OCC(=O)c3ccccc3)c(C)c21

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PDE4B Q07343 1/20 0.31
HSD11B1 P28845 1/20 0.31
CA12 O43570 1/20 0.30
CA9 Q16790 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8622570 1.00 PDE4B (0.31) PDE4BHSD11B1CA12CA9HPGD
SCHEMBL8462335 0.93 NPC1 (0.32) PDE4BHSD11B1CA12CA9HPGD
SCHEMBL8462328 0.93 NPC1 (0.32) PDE4BHSD11B1CA12CA9HPGD
SCHEMBL8615782 0.83 POLB (0.34)
SCHEMBL8616405 0.83 POLB (0.34)
SCHEMBL8462284 0.82 NPC1 (0.31) HPGD
SCHEMBL8462291 0.82 NPC1 (0.31) HPGD
SCHEMBL9038689 0.81 POLB (0.30)
SCHEMBL8619538 0.80 ALDH1A1 (0.31)
SCHEMBL8619329 0.80 LMNA (0.33) PDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5849926-A Pyrazole derivatives and herbicides containing the same IDEMITSU KOSAN CO., LTD. (JP) 1998-12-15 US disclosed