Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | MPI | P34949 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6712518 | 0.84 | MAPT (0.63) | MAPTALDH1A1POLBMAPK1TDP1 | |
| SCHEMBL4848969 | 0.82 | NAMPT (0.58) | MAPTALDH1A1POLBMAPK1MPI | |
| SCHEMBL6632472 | 0.81 | POLB (0.79) | MAPTALDH1A1POLBMAPK1MPI | |
| SCHEMBL28121312 | 0.81 | PTPRF (0.71) | MAPTALDH1A1POLBMAPK1TDP1 | |
| SCHEMBL9003269 | 0.79 | MAPT (0.70) | MAPTALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL11401029 | 0.78 | POLB (0.73) | MAPTALDH1A1POLBL3MBTL1SMN1; SMN2 | |
| SCHEMBL4951837 | 0.76 | ALDH1A1 (0.73) | MAPTALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL14064827 | 0.75 | RAD52 (0.52) | MAPTALDH1A1MAPK1L3MBTL1SMN1; SMN2 | |
| SCHEMBL4843988 | 0.75 | ALDH1A1 (0.61) | MAPTALDH1A1POLBMAPK1TDP1 | |
| SCHEMBL14117517 | 0.74 | ALDH1A1 (0.66) | MAPTALDH1A1SMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852045-A | Fibrinogen receptor antagonists | MERCK & CO., INC. (US) | 1998-12-22 | — | — | US | disclosed |