SCHEMBL8622747

SCHEMBL8622747

CC(Cl)C(=O)NNc1ccccc1

nearest known ligand 0.72

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GAA P10253 11/20 0.72
SMN1; SMN2 Q16637 5/20 0.60
LMNA P02545 3/20 0.60
ALOX5 P09917 2/20 0.57
CYP3A4 P08684 1/20 0.57
TSHR P16473 1/20 0.57
ALDH1A1 P00352 6/20 0.54
PKM P14618 1/20 0.53
PTGS2 P35354 2/20 0.50
KDM4E B2RXH2 1/20 0.50
ATM Q13315 2/20 0.49
MAPT P10636 2/20 0.49
HSP90AA1 P07900 2/20 0.47
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
GPR55 Q9Y2T6 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6570519 0.84 GAA (1.00) GAASMN1; SMN2LMNAALOX5CYP3A4
SCHEMBL27822637 0.81 GAA (0.72) GAASMN1; SMN2LMNAALOX5CYP3A4
SCHEMBL2516508 0.80 ALDH1A1 (0.67) GAASMN1; SMN2LMNATSHRALDH1A1
Water SCHEMBL27691964 0.78 ALDH1A1 (0.65) GAASMN1; SMN2LMNATSHRALDH1A1
SCHEMBL10434862 0.78 GAA (0.68) GAASMN1; SMN2LMNAALOX5CYP3A4
SCHEMBL10135121 0.78 GAA (0.68) GAASMN1; SMN2LMNAALOX5CYP3A4
SCHEMBL10117735 0.78 GAA (0.68) GAASMN1; SMN2LMNAALOX5CYP3A4
SCHEMBL8113450 0.77 GAA (0.66) GAASMN1; SMN2LMNAALOX5CYP3A4
SCHEMBL9188482 0.76 GAA (0.66) GAASMN1; SMN2LMNAALOX5CYP3A4
SCHEMBL14019910 0.73 GAA (0.61) GAASMN1; SMN2LMNAALOX5CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105418506-A Acetobenzylamide piperazine derivative and application thereof as cranial nerve protective agent SHANGHAI INST PHARMACEUTICAL IND 2016-03-23 CN disclosed
EP-0464612-B1 Silver halide photographic materials FUJI PHOTO FILM CO LTD (JP) 1998-05-13 EP disclosed
US-5529894-A PYRAZOLOAZOLE BASED MAGENTA COUPLER, TIMING COUPLER; SHARPNESS, DESILVERING PROPERTIES FUJI PHOTO FILM CO., LTD. (JP) 1996-06-25 US disclosed
EP-0438150-B1 Silver halide colour photographic material FUJI PHOTO FILM CO LTD (JP) 1995-04-26 EP disclosed
EP-0438129-B1 Silver halide color photographic material FUJI PHOTO FILM CO LTD (JP) 1995-04-12 EP disclosed
US-5360709-A Silver halide photographic material containing a DIR compound FUJI PHOTO FILM CO., LTD. (JP) 1994-11-01 US disclosed
US-5350666-A Silver halide photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1994-09-27 US disclosed
EP-0464612-A1 Silver halide photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1992-01-08 EP disclosed
EP-0438150-A2 Silver halide colour photographic material FUJI PHOTO FILM CO., LTD. (JP) 1991-07-24 EP disclosed
EP-0438129-A2 Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1991-07-24 EP disclosed