Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 8/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9879981 | 0.85 | MAPT (0.49) | HDAC2HDAC8HDAC1HDAC3HDAC6 | |
| SCHEMBL6618522 | 0.85 | MAPT (0.49) | HDAC2HDAC8HDAC1HDAC3HDAC6 | |
| SCHEMBL8622951 | 0.84 | ALOX5 (0.48) | HDAC2HDAC8HDAC1HDAC3HDAC6 | |
| SCHEMBL8323870 | 0.81 | ALDH1A1 (0.40) | MEN1KMT2AEPHX2 | |
| SCHEMBL8880376 | 0.81 | EPHX2 (0.54) | HDAC2HDAC8HDAC1HDAC3HDAC6 | |
| SCHEMBL7739753 | 0.80 | CCR6 (0.41) | HDAC2HDAC8HDAC1HDAC3HDAC6 | |
| SCHEMBL8989023 | 0.80 | CCR6 (0.41) | HDAC2HDAC8HDAC1HDAC3HDAC6 | |
| SCHEMBL2906610 | 0.80 | HDAC3 (0.46) | HDAC2HDAC8HDAC1HDAC3HDAC6 | |
| SCHEMBL6951407 | 0.80 | HTT (0.44) | HDAC2HDAC8HDAC1HDAC3HDAC6 | |
| SCHEMBL8989037 | 0.80 | L3MBTL1 (0.37) | HDAC2HDAC8HDAC1HDAC3HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815084-B1 | LACTAM-CONTAINING HYDROXAMIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF MATRIX METALLOPROTEASE | PROCTER & GAMBLE (US) | 2003-08-27 | — | — | EP | disclosed |
| US-5672598-A | MATRIX METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 1997-09-30 | — | — | US | disclosed |