SCHEMBL8623155

SCHEMBL8623155

C[Si](C)(C)OC1CC(=O)OC(=O)C1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8626005 0.80 SMN1; SMN2 (0.30) SMN1; SMN2
SCHEMBL8618206 0.79
SCHEMBL1295672 0.79 BUB1 (0.34)
SCHEMBL12900035 0.77 PTPN1 (0.38) SMN1; SMN2
SCHEMBL8621965 0.76
SCHEMBL14546385 0.75 TSHR (0.36) TSHRSMN1; SMN2
SCHEMBL10531612 0.74 SORT1 (0.30)
SCHEMBL8623059 0.73
SCHEMBL8623069 0.73 ALDH1A1 (0.35) TSHR
SCHEMBL19676622 0.73 SMN1; SMN2 (0.52) SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0608132-B1 Coating varnish composition and antifouling coating composition HITACHI CHEMICAL CO LTD (JP) 1998-05-20 EP disclosed
US-5439511-A Composition containing polymer obtained by polymerizing unsaturated acid anhydride and another unsaturated compound, specified additive HITACHI CHEMICAL COMPANY, LTD. (JP) 1995-08-08 US disclosed
EP-0608132-A1 Coating varnish composition and antifouling coating composition HITACHI CHEMICAL CO., LTD. (JP) 1994-07-27 EP disclosed