SCHEMBL1295672

SCHEMBL1295672

CC(C)(C)[Si](C)(C)OC1CC(=O)OC(=O)C1

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
BUB1 O43683 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isopropylamine SCHEMBL7802561 0.90 BUB1 (0.31) BUB1
Diethylamine SCHEMBL7801610 0.87 BUB1 (0.32) BUB1
SCHEMBL1799927 0.83 BUB1 (0.36) BUB1
SCHEMBL9229380 0.81 PTPN1 (0.35) BUB1
Benzylamine SCHEMBL7801517 0.80 BUB1 (0.37) BUB1
SCHEMBL18320267 0.80 BUB1 (0.34) BUB1
Phenethylamine SCHEMBL7800218 0.79 HTR2A (0.40) BUB1
SCHEMBL8623155 0.79 TSHR (0.33)
SCHEMBL3999602 0.78 CRBN (0.40) BUB1
Phenethylamine SCHEMBL7802643 0.78 HTR2A (0.39) BUB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119189484-B Phenolic resin-based copper-clad plate filled with boron nitride micro powder and preparation method thereof 江苏耀鸿电子有限公司 2025-06-17 CN claimed
CN-119189484-A Phenolic resin-based copper-clad plate filled with boron nitride micro powder and preparation method thereof 江苏耀鸿电子有限公司 2024-12-27 CN claimed
CN-118931032-A Aging-resistant woven bag and preparation process thereof 温州隆庆塑业有限公司 2024-11-12 CN claimed
CN-114874106-B Amino lipid and preparation method and application thereof 中山大学附属第七医院(深圳) 2023-04-14 CN claimed
CN-114874106-A Amino lipid and preparation method and application thereof 中山大学附属第七医院(深圳) 2022-08-09 CN claimed
CN-111484611-B Polyethylene glycol polymer containing thioester and aldehyde group, preparation method thereof, chemically crosslinked hydrogel containing same and application 复旦大学 2022-06-07 CN claimed
CN-114395435-A High-temperature-resistant coking-carbon-deposition-resistant high-bearing gear oil 广州诺拜因化工有限公司 2022-04-26 CN claimed
CN-114106907-A Composite lithium-based grease type damping high-temperature bearing lubricant 广州诺拜因化工有限公司 2022-03-01 CN claimed
CN-112280327-A Carbon nanotube doped plant fiber type high polymer material and preparation method thereof 华碳创新(广东)材料技术有限公司 2021-01-29 CN claimed
CN-112251041-A Reinforced polyethylene wood-plastic material containing carbon nano tubes and preparation method thereof 华碳创新(广东)材料技术有限公司 2021-01-22 CN claimed
CN-111484611-A Polyethylene glycol polymer containing thioester and aldehyde group, preparation method thereof, chemical crosslinking hydrogel containing thioester and aldehyde group and application of chemical crosslinking hydrogel 复旦大学 2020-08-04 CN claimed
US-6113678-A Hot melt inks containing polyanhydrides XEROX CORPORATION (US) 2000-09-05 US claimed
US-5919552-A Coated substrates and methods XEROX CORPORATION (US) 1999-07-06 US claimed
US-12637405-B2 Integrated process for generating acid anhydrides CLEANTECH BUILDING MATERIALS PLC (GB) 2026-05-26 US disclosed
US-20250304521-A1 PROCESS FOR GENERATING ACID ANHYDRIDES CLEANTECH BUILDING MATERIALS PLC (GB) 2025-10-02 US disclosed
US-12358860-B2 Process for generating acid anhydrides CLEANTECH BUILDING MATERIALS PLC (GB) 2025-07-15 US disclosed
EP-0340007-A2 Process for preparing a ketophosphonate intermediate useful in preparing HMG-CoA reductase inhibitors E.R. SQUIBB & SONS, INC. (US) 1989-11-02 EP disclosed
WO-1989004821-A1 N-(BIPHENYLMETHYL)-3-HYDROXYGLUTARAMIC ACID AND DERIVATIVES AS HYPOCHOLESTEROLEMIC AGENTS PFIZER INC. (US) 1989-06-01 WO disclosed
EP-0318181-A2 N-(Biphenylmethyl)-3-hydroxyglutaramic acids and derivatives as hypocholesterolemic agents PFIZER INC. (US) 1989-05-31 EP disclosed
US-4804770-A Process for preparing a keto-phosphonate intermediate useful in preparing HMG-CoA reductase inhibitors E. R. SQUIBB & SONS, INC. (US) 1989-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250304521-A1 PROCESS FOR GENERATING ACID ANHYDRIDES CA1, CA9, CA6 BUB1 4559/4885
US-12358860-B2 Process for generating acid anhydrides CA1, CA9, CA6 BUB1 4559/4885
US-12637405-B2 Integrated process for generating acid anhydrides GRHPR, GCDH, OGDH BUB1 4713/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.