Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | ITGAV | P06756 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8623091 | 0.83 | ITGB3 (0.47) | ITGB3ITGA2BITGAV | |
| SCHEMBL8616963 | 0.80 | HRH3 (0.47) | KMT2AALDH1A1 | |
| SCHEMBL8623787 | 0.74 | HRH3 (0.42) | KMT2ASRCALDH1A1 | |
| SCHEMBL8620203 | 0.73 | ITGB3 (0.41) | KMT2AITGB3ITGA2BSRCALDH1A1 | |
| SCHEMBL8623903 | 0.67 | ITGB3 (0.52) | ITGB3ITGA2B | |
| SCHEMBL7371673 | 0.66 | ITGB3 (0.51) | KMT2AITGB3ITGA2BALDH1A1 | |
| SCHEMBL8624634 | 0.65 | HRH3 (0.44) | KMT2AALDH1A1 | |
| SCHEMBL8617256 | 0.65 | ITGB3 (0.42) | ITGB3ITGA2B | |
| SCHEMBL1144523 | 0.65 | KMT2A (0.55) | KMT2AALDH1A1ROCK2ROCK1 | |
| SCHEMBL1460374 | 0.65 | KMT2A (0.55) | KMT2AALDH1A1ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852045-A | Fibrinogen receptor antagonists | MERCK & CO., INC. (US) | 1998-12-22 | — | — | US | disclosed |