Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.42 |
| ▸ | SRC | P12931 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8616963 | 0.93 | HRH3 (0.47) | HRH3CYP19A1TDP1L3MBTL1CHRNB1 | |
| SCHEMBL8623903 | 0.78 | ITGB3 (0.52) | — | |
| SCHEMBL8619188 | 0.76 | HRH3 (0.38) | HRH3SRCCYP19A1FAAHCHRM3 | |
| SCHEMBL8620203 | 0.75 | ITGB3 (0.41) | HRH3SRCMEN1ALDH1A1KMT2A | |
| SCHEMBL8623253 | 0.74 | KMT2A (0.41) | SRCALDH1A1KMT2A | |
| SCHEMBL8624634 | 0.71 | HRH3 (0.44) | HRH3TDP1L3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL7371673 | 0.70 | ITGB3 (0.51) | HRH3TDP1L3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL8617256 | 0.69 | ITGB3 (0.42) | HRH3CYP19A1TDP1L3MBTL1CYP1A2 | |
| SCHEMBL7322436 | 0.68 | HRH3 (0.40) | HRH3CYP19A1CHRM3KDM4EMEN1 | |
| SCHEMBL2567758 | 0.66 | ALDH1A1 (0.49) | SRCL3MBTL1KDM4EALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852045-A | Fibrinogen receptor antagonists | MERCK & CO., INC. (US) | 1998-12-22 | — | — | US | disclosed |