Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.55 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2624372 | 0.86 | GAA (0.62) | GAANPSR1ALDH1A1TSHRKDM4E | |
| SCHEMBL5881684 | 0.84 | AKR1C3 (0.73) | NPSR1AKR1C3AKR1C2PTGS2ALDH1A1 | |
| SCHEMBL24675593 | 0.83 | GAA (0.59) | GAANPSR1ALDH1A1TSHRKDM4E | |
| SCHEMBL10282672 | 0.83 | ALDH1A1 (0.69) | GAANPSR1ALDH1A1TSHRKDM4E | |
| SCHEMBL6577434 | 0.83 | GAA (0.59) | GAANPSR1ALDH1A1TSHRKDM4E | |
| SCHEMBL8631023 | 0.83 | GAA (0.59) | GAANPSR1ALDH1A1TSHRKDM4E | |
| SCHEMBL12742268 | 0.82 | GAA (0.57) | GAANPSR1ALDH1A1TSHRKDM4E | |
| Hydrochloric Acid SCHEMBL29823025 | 0.82 | GAA (0.57) | GAANPSR1ALDH1A1TSHRKDM4E | |
| SCHEMBL14033993 | 0.81 | MAPT (0.56) | GAANPSR1ALDH1A1TSHRKDM4E | |
| SCHEMBL4633972 | 0.81 | NPC1 (0.62) | NPSR1AKR1C3AKR1C2PTGS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817677-A | ANTITHROMBOSIS AGENTS | DR. KARL THOMAE GMBH (DE) | 1998-10-06 | — | — | US | disclosed |