Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.49 |
| ▸ | DDO | Q99489 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30095711 | 1.00 | DAO (0.49) | DAODDOKMT2AKDM4EHPGD | |
| SCHEMBL29162197 | 0.78 | DAO (0.39) | DAODDOKMT2AKDM4EHPGD | |
| SCHEMBL15875649 | 0.78 | DAO (0.49) | DAODDOKDM4EHPGDALDH1A1 | |
| SCHEMBL15875625 | 0.78 | TDP1 (0.46) | KDM4EHPGDALDH1A1TSHRHSD17B10 | |
| SCHEMBL8619858 | 0.78 | NOS1 (0.52) | DAOKMT2AKDM4EHPGDALDH1A1 | |
| SCHEMBL25415892 | 0.78 | IMPDH2 (0.43) | DAODDOKDM4EHPGDALDH1A1 | |
| SCHEMBL30878033 | 0.78 | NOS1 (0.52) | DAOKMT2AKDM4EHPGDALDH1A1 | |
| SCHEMBL3171494 | 0.74 | KDM4E (0.33) | DAODDOKMT2AKDM4EHPGD | |
| SCHEMBL16108649 | 0.74 | ABCG2 (0.50) | KMT2AKDM4EHPGDALDH1A1NPC1 | |
| SCHEMBL30306363 | 0.74 | PBRM1 (0.50) | KMT2AKDM4EHPGDALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117480155-A | Diacylglycerol kinase modulating compounds | 吉利德科学公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-113754595-A | Preparation method and application of 6-fluoroquinazoline derivatives containing disulfide structures | 贵州大学 | 2021-12-07 | — | — | CN | disclosed |
| US-5849861-A | Polyquinazolines and methods for their preparation | HITACHI CHEMICAL CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |
| US-5686560-A | TREATING A MONOMER WITH A BASE IN A DIPOLAR SOLVENT | HITACHI CHEMICAL CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |