Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 3/20 | 0.39 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8623931 | 0.78 | DAO (0.49) | DAOKDM4EKMT2AHSD17B10PARP1 | |
| SCHEMBL30095711 | 0.78 | DAO (0.49) | DAOKDM4EKMT2AHSD17B10PARP1 | |
| SCHEMBL7215930 | 0.70 | MEN1 (0.35) | KDM4EKMT2AHSD17B10MEN1CASP1 | |
| SCHEMBL3171494 | 0.70 | KDM4E (0.33) | DAOKDM4EKMT2AMEN1PARP1 | |
| SCHEMBL1287813 | 0.69 | KDM4E (0.46) | KDM4EKMT2AHSD17B10MEN1CASP1 | |
| SCHEMBL31411470 | 0.68 | TRPA1 (0.50) | HPGDHTTMETAP2 | |
| SCHEMBL31184676 | 0.68 | DAO (0.38) | DAOKDM4EALDH1A1HPGDPDE3B | |
| SCHEMBL31184602 | 0.68 | LMNA (0.37) | DAOPARP1ALDH1A1HPGDPDE3B | |
| SCHEMBL31184823 | 0.68 | ALDH1A1 (0.39) | KDM4EHSD17B10PARP1ALDH1A1HPGD | |
| SCHEMBL30424493 | 0.68 | KDM4E (0.35) | DAOKDM4EKMT2AHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4359389-A1 | DIACYLGLYERCOL KINASE MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2024-05-01 | — | — | EP | disclosed |
| CN-117480155-A | Diacylglycerol kinase modulating compounds | 吉利德科学公司 | 2024-01-30 | — | — | CN | disclosed |
| WO-2022271677-A1 | DIACYLGLYERCOL KINASE MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2022-12-29 | — | — | WO | disclosed |