Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPY1R | P25929 | 1/20 | 0.46 |
| ▸ | NPY2R | P49146 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13793643 | 0.88 | MCL1 (0.53) | MAPTALDH1A1GAAL3MBTL1MRGPRX4 | |
| SCHEMBL8623315 | 0.87 | POLB (0.47) | MAPTGAAL3MBTL1KMT2AMEN1 | |
| SCHEMBL8590581 | 0.82 | MAPT (0.45) | MAPTALDH1A1GAAL3MBTL1MRGPRX4 | |
| SCHEMBL1539419 | 0.82 | ACHE (0.40) | L3MBTL1MRGPRX4KMT2AHTR2AMAOA | |
| SCHEMBL12894385 | 0.81 | MAPT (0.46) | MAPTALDH1A1GAAL3MBTL1MRGPRX4 | |
| SCHEMBL2556977 | 0.81 | MAPT (0.49) | MAPTALDH1A1GAAL3MBTL1MRGPRX4 | |
| SCHEMBL9306893 | 0.79 | MRGPRX4 (0.68) | ALDH1A1L3MBTL1MRGPRX4MCL1KMT2A | |
| SCHEMBL1539409 | 0.78 | LMNA (0.50) | MAPTALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL8622099 | 0.78 | MAOB (0.47) | MAPTNPC1RAB9AHTR1AHTR2A | |
| SCHEMBL8622258 | 0.78 | MAOB (0.47) | MAPTALDH1A1GAAKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0658541-B1 | PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO (JP) | 1998-05-20 | — | — | EP | disclosed |
| US-5510506-A | Process for producing carboxylic acid derivatives | SHIONOGI & CO., LTD. (JP) | 1996-04-23 | — | — | US | disclosed |
| EP-0658541-A1 | PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1995-06-21 | — | — | EP | disclosed |