Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 16/20 | 0.48 |
| ▸ | CCR2 | P41597 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6768750 | 0.83 | HRH3 (0.55) | CCR5CCR2CHRM1 | |
| SCHEMBL6770020 | 0.79 | KMT2A (0.58) | CCR2 | |
| SCHEMBL6768747 | 0.72 | MEN1 (0.53) | CCR2 | |
| SCHEMBL6765593 | 0.71 | CCR2 (0.57) | CCR5CCR2OPRM1OPRL1 | |
| SCHEMBL8572593 | 0.70 | CCR2 (0.56) | CCR5CCR2OPRM1OPRL1 | |
| SCHEMBL6703958 | 0.70 | CCR5 (0.74) | CCR5 | |
| SCHEMBL12333385 | 0.68 | HRH4 (0.55) | CHRM1 | |
| SCHEMBL8565906 | 0.68 | CCR2 (0.54) | CCR5CCR2OPRM1OPRL1 | |
| SCHEMBL8565792 | 0.68 | CCR2 (0.54) | CCR5CCR2OPRM1OPRL1 | |
| SCHEMBL15966084 | 0.68 | KMT2A (0.68) | CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997044329-A9 | DIARYLALKYL CYCLIC DIAMINE DERIVATIVES AS CHEMOKINE RECEPTOR ANTAGONISTS | — | 1998-03-12 | — | — | WO | disclosed |