Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 7/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 6/20 | 0.31 |
| ▸ | KDM1A | O60341 | 4/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.31 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL513026 | 0.98 | TSHR (0.38) | TSHRBRD4MAOBALDH1A1HSD17B10 | |
| SCHEMBL383636 | 0.79 | — | — | |
| SCHEMBL28529394 | 0.79 | — | — | |
| SCHEMBL27305409 | 0.78 | MAPT (0.43) | MAOBMAOAHTR2C | |
| SCHEMBL27300497 | 0.78 | POLB (0.33) | SMN1; SMN2MAOALMNACYP2A6SLC6A2 | |
| SCHEMBL5574180 | 0.78 | ALDH1A1 (0.36) | ALDH1A1HSD17B10MAOAKDM1ACYP2C9 | |
| SCHEMBL27871634 | 0.77 | TSHR (0.40) | TSHRMAOBALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL3949365 | 0.76 | L3MBTL1 (0.47) | TSHRALDH1A1HSD17B10SMN1; SMN2LMNA | |
| SCHEMBL14675631 | 0.76 | — | — | |
| SCHEMBL27306688 | 0.76 | KDM4E (0.41) | MAOBMAOAKDM1ACYP2D6SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101979415-B | Polyhedral-modified polymer | BRIDGESTONE CORP | 2012-06-13 | — | — | CN | disclosed |
| CN-101979415-A | Polyhedral-modified polymer | BRIDGESTONE CORP | 2011-02-23 | — | — | CN | disclosed |
| CN-101094892-B | Polyhedral Modified Polymers | BRIDGESTONE CORP | 2010-12-08 | — | — | CN | disclosed |
| CN-101094892-A | Polyhedral Modified Polymers | BRIDGESTONE CORP (JP) | 2007-12-26 | — | — | CN | disclosed |
| US-5767288-A | DITHIANE-BENZOIN ADDUCTS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1998-06-16 | — | — | US | disclosed |