Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 4/20 | 0.62 |
| ▸ | PGR | P06401 | 6/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.49 |
| ▸ | TUBB | P07437 | 1/20 | 0.49 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.49 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.49 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.49 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.49 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.49 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.49 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.49 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.49 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.49 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.49 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.49 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.49 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7006004 | 0.87 | TUBB4A (0.60) | SLC40A1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL8623477 | 0.86 | SLC40A1 (0.59) | SLC40A1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL8624193 | 0.85 | SLC40A1 (0.62) | SLC40A1HPGDHTTTUBB4ATUBB | |
| SCHEMBL8623534 | 0.80 | KMT2A (0.60) | SLC40A1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL3171049 | 0.79 | SLC40A1 (0.71) | SLC40A1PGRG6PDNFKBIAAGTR1 | |
| SCHEMBL8623678 | 0.79 | SLC40A1 (0.61) | SLC40A1PGRNPC1HPGDHTT | |
| SCHEMBL8623512 | 0.79 | TUBB4A (0.74) | SLC40A1HTTTUBB4ATUBBTUBA3C | |
| SCHEMBL8623823 | 0.79 | TUBB4A (0.61) | SLC40A1NPC1HTTTUBB4ATUBB | |
| SCHEMBL8624412 | 0.78 | CA12 (0.63) | HTTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6980378 | 0.77 | SLC40A1 (1.00) | SLC40A1G6PDNFKBIAAGTR1METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0472053-B1 | Sulfonamide derivatives | EISAI CO LTD (JP) | 1998-06-17 | — | — | EP | disclosed |
| CN-1036650-C | process for the preparation of sulfonamide derivatives | EISAI CO LTD (JP) | 1997-12-10 | — | — | CN | disclosed |
| US-5610304-A | Pyrimidinyl or pyridinyl sulfonamide substituted compounds | EISAI CO., LTD. (JP) | 1997-03-11 | — | — | US | disclosed |
| US-5610320-A | ANTITUMOR AGENTS | EISAI CO., LTD. (JP) | 1997-03-11 | — | — | US | disclosed |
| CN-1136036-A | Sulfonamide derivatives | EISAI CO LTD (JP) | 1996-11-20 | — | — | CN | disclosed |
| US-5434172-A | Antitumor | EISAI CO., LTD. (JP) | 1995-07-18 | — | — | US | disclosed |
| US-5332751-A | Antitumor | EISAI CO., LTD. (JP) | 1994-07-26 | — | — | US | disclosed |
| US-5292758-A | Sulfonamide derivatives | EISAI CO., LTD. (JP) | 1994-03-08 | — | — | US | disclosed |
| US-5250549-A | Antitumor agents | EISAI CO., LTD. (JP) | 1993-10-05 | — | — | US | disclosed |
| EP-0472053-A2 | Sulfonamide derivatives | Eisai Co., Ltd. (JP) | 1992-02-26 | — | — | EP | disclosed |