Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 5/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11725386 | 0.73 | CRBN (0.40) | CRBNDDB1LMNAHTTNPSR1 | |
| SCHEMBL9614983 | 0.73 | CRBN (0.37) | CRBNDDB1LMNAHTTNPSR1 | |
| SCHEMBL16865428 | 0.72 | MMP9 (0.56) | ATMSMN1; SMN2CYP3A4MMP9MMP8 | |
| SCHEMBL11724574 | 0.71 | HTT (0.37) | CRBNDDB1LMNAHTTNPSR1 | |
| SCHEMBL27831127 | 0.71 | L3MBTL1 (0.41) | CRBNDDB1LMNAHTTNPSR1 | |
| SCHEMBL4749681 | 0.69 | TSHR (0.36) | CRBNDDB1LMNANPSR1KDM4E | |
| SCHEMBL13967211 | 0.69 | CYP3A4 (0.41) | CRBNDDB1HTTATMSMN1; SMN2 | |
| SCHEMBL11281090 | 0.69 | DDB1 (0.36) | CRBNDDB1LMNAHTTNPSR1 | |
| SCHEMBL21646073 | 0.69 | HTT (0.49) | LMNAHTTNPSR1L3MBTL1SMN1; SMN2 | |
| SCHEMBL11208493 | 0.69 | NPSR1 (0.66) | LMNAHTTNPSR1L3MBTL1TOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10168058-A | — | — | None | — | — | JP | disclosed |
| JP-3200762-A | — | — | None | — | — | JP | disclosed |
| JP-H10168058-A | PRODUCTION OF OPTICALLY ACTIVE 1-BENZYL-3-HYDROXYPYRROLIDINE | KOEI CHEM CO LTD | 1998-06-23 | — | — | JP | disclosed |
| JP-H03200762-A | PRODUCTION OF 1-BENZYL-3-PYRROLIDINOL | KANEGAFUCHI CHEM IND CO LTD | 1991-09-02 | — | — | JP | disclosed |