Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 9/20 | 0.52 |
| ▸ | CTSG | P08311 | 6/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | SLC37A4 | O43826 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10490983 | 0.85 | CES2 (0.63) | ELANECTSGCES2 | |
| SCHEMBL10630402 | 0.78 | CES2 (0.52) | ELANECTSGCES2 | |
| SCHEMBL10634752 | 0.76 | CES2 (0.50) | ELANECTSGCES2SLC37A4 | |
| SCHEMBL8077270 | 0.72 | CES2 (0.50) | ELANECTSGCES2 | |
| SCHEMBL8425316 | 0.69 | CES2 (0.39) | CES2SLC37A4 | |
| SCHEMBL9629596 | 0.68 | CES2 (0.51) | ELANECTSGCES2 | |
| SCHEMBL9628696 | 0.68 | CES2 (0.51) | ELANECTSGCES2 | |
| SCHEMBL8077268 | 0.68 | CES2 (0.45) | ELANECTSGCES2 | |
| SCHEMBL8425196 | 0.68 | CES2 (0.38) | CES2 | |
| SCHEMBL9700567 | 0.67 | CES2 (0.52) | CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5844004-A | 10-substituted 1,8-dihydroxy-9 (10H) anthracenone pharmaceuticals | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 1998-12-01 | — | — | US | disclosed |