Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 3/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.43 |
| ▸ | CTSG | P08311 | 2/20 | 0.42 |
| ▸ | POLM | Q9NP87 | 1/20 | 0.42 |
| ▸ | POLK | Q9UBT6 | 1/20 | 0.42 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.42 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.42 |
| ▸ | SLC37A4 | O43826 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10490983 | 0.86 | CES2 (0.63) | CES2ELANECTSGMEN1ALDH1A1 | |
| SCHEMBL10630402 | 0.86 | CES2 (0.52) | CES2ELANECTSGMEN1LMNA | |
| SCHEMBL10628386 | 0.82 | PIM1 (0.43) | KDM4EMEN1ABCC4USP2ALDH1A1 | |
| SCHEMBL10634901 | 0.79 | PIM1 (0.46) | KDM4EMEN1ABCC4USP2ALDH1A1 | |
| SCHEMBL24072440 | 0.76 | PPARG (0.43) | CES2ELANEPPARGPPARAPTGS2 | |
| SCHEMBL8624814 | 0.76 | ELANE (0.52) | CES2ELANECTSGSLC37A4 | |
| SCHEMBL10634860 | 0.75 | PTPN1 (0.43) | CES2MEN1LMNACHRM2ADRA2A | |
| SCHEMBL10779985 | 0.74 | KDM4E (0.46) | ELANEPPARGPPARAPTGS2KDM4E | |
| SCHEMBL9538649 | 0.73 | MEN1 (0.64) | ELANECTSGKDM4EMEN1ABCC4 | |
| SCHEMBL8077270 | 0.73 | CES2 (0.50) | CES2ELANECTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4755530-A | 1-hydroxy-8-acyloxy-10-acyl anthrones, process for their preparation and their use in human or veterinary medicines and in cosmetic formulations | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (C.I.R.D) (FR) | 1988-07-05 | — | — | US | disclosed |