Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 17/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 16/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8619999 | 0.96 | HRH4 (0.61) | HRH4HRH3TP53CYP1A2CYP3A4 | |
| SCHEMBL8620794 | 0.89 | HRH3 (0.56) | HRH4HRH3TP53CYP1A2CYP3A4 | |
| SCHEMBL8625836 | 0.86 | HRH3 (0.63) | HRH4HRH3TP53CYP1A2CYP3A4 | |
| SCHEMBL8621926 | 0.86 | HRH3 (0.60) | HRH4HRH3TP53CYP1A2CYP3A4 | |
| SCHEMBL8619886 | 0.85 | HRH4 (0.61) | HRH4HRH3TP53CYP1A2CYP3A4 | |
| SCHEMBL8618191 | 0.85 | HRH3 (0.62) | HRH4HRH3TP53CYP1A2CYP3A4 | |
| SCHEMBL8805742 | 0.81 | HRH4 (0.54) | HRH4HRH3TP53CYP1A2CYP3A4 | |
| SCHEMBL8808473 | 0.76 | HRH4 (0.56) | HRH4HRH3TP53CYP1A2CYP3A4 | |
| Bromide SCHEMBL11657850 | 0.75 | HRH4 (0.46) | HRH4HRH3TAAR1TBXAS1 | |
| SCHEMBL8805366 | 0.74 | HRH4 (0.63) | HRH4HRH3TP53CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5837718-A | ANTIHISTAMINES | SEED CAPITAL INVESTMENT (SCI) B.V. (NL) | 1998-11-17 | — | — | US | disclosed |