Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 1/20 | 0.42 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.42 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.42 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.34 |
| ▸ | TNF | P01375 | 2/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8619019 | 0.91 | ABCC9 (0.51) | ABCC9ABCC8KCNJ11KCNJ8PDK1 | |
| SCHEMBL4261010 | 0.79 | ABCC9 (0.40) | ABCC9ABCC8KCNJ11KCNJ8PDK1 | |
| SCHEMBL8622441 | 0.78 | PDK1 (0.38) | ABCC9ABCC8KCNJ11KCNJ8PDK1 | |
| SCHEMBL7894099 | 0.77 | ABCC9 (0.50) | ABCC9ABCC8KCNJ11KCNJ8PDK1 | |
| SCHEMBL8667527 | 0.72 | ABCC9 (0.51) | ABCC9ABCC8KCNJ11KCNJ8HSD11B1 | |
| SCHEMBL8624137 | 0.69 | ABCC9 (0.41) | ABCC9ABCC8KCNJ11KCNJ8SLC22A12 | |
| SCHEMBL8420167 | 0.69 | ABCC9 (0.48) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL26916884 | 0.68 | LMNA (0.58) | PDK1PDK2PDK3PDK4HSD11B1 | |
| SCHEMBL26620605 | 0.68 | LMNA (0.58) | PDK1PDK2PDK3PDK4HSD11B1 | |
| SCHEMBL7895113 | 0.68 | ABCC9 (0.60) | ABCC9ABCC8KCNJ11KCNJ8PDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780505-A | ADMINISTERING AS SMOOTH MUSCLE RELAXANT | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-07-14 | — | — | US | claimed |