SCHEMBL8625006

SCHEMBL8625006

C=CC(Oc1cccc(C=O)c1)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 7/20 0.49
MAOB P27338 7/20 0.49
UNG P13051 1/20 0.45
SRC P12931 1/20 0.44
NPC1 O15118 4/20 0.40
RAB9A P51151 3/20 0.40
DRD1 P21728 1/20 0.40
TRIM24 O15164 1/20 0.40
TRIM33 Q9UPN9 1/20 0.40
ALDH1A1 P00352 2/20 0.39
CYP2A6 P11509 1/20 0.39
KMT2A Q03164 2/20 0.39
GAA P10253 1/20 0.39
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
TDP1 Q9NUW8 1/20 0.38
POLB P06746 2/20 0.38
MEN1 O00255 1/20 0.38
BLM P54132 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8625767 0.82 ALDH1A3 (0.50) RAB9ADRD1ALDH1A1CYP2A6KMT2A
SCHEMBL7284897 0.79 MAOA (0.50) MAOAMAOBUNGSRCNPC1
SCHEMBL3291158 0.79 SLC6A4 (0.39) ALDH1A1MAPT
SCHEMBL3293320 0.79 RXRA (0.46) MAOAMAOBDRD1
SCHEMBL592586 0.79 SRC (0.47) MAOAMAOBUNGSRCNPC1
SCHEMBL2554873 0.78 MAOA (0.49) MAOAMAOBUNGSRCNPC1
SCHEMBL3295618 0.78 MAOB (0.44) MAOBNPC1RAB9AALDH1A1KMT2A
SCHEMBL28190798 0.78 SRC (0.46) MAOAMAOBUNGSRCNPC1
SCHEMBL9059708 0.77 MAOA (0.54) MAOAMAOBUNGSRCNPC1
SCHEMBL8625768 0.76 PTGIR (0.41) MAOAMAOBKMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0597510-B1 Biologically active reagent prepared from aldehyde-containing polymer, test kit, analytical element and methods of use JOHNSON & JOHNSON CLIN DIAG (US) 1998-06-10 EP claimed
US-5401633-A Immunology, label detection EASTMAN KODAK COMPANY (US) 1995-03-28 US claimed
EP-0597510-A1 Biologically active reagent prepared from aldehyde-containing polymer, test kit, analytical element and methods of use Johnson & Johnson Clinical Diagnostics, Inc. (US) 1994-05-18 EP claimed
EP-0597510-B1 Biologically active reagent prepared from aldehyde-containing polymer, test kit, analytical element and methods of use JOHNSON & JOHNSON CLIN DIAG (US) 1998-06-10 EP disclosed
US-5401633-A Immunology, label detection EASTMAN KODAK COMPANY (US) 1995-03-28 US disclosed
EP-0597510-A1 Biologically active reagent prepared from aldehyde-containing polymer, test kit, analytical element and methods of use Johnson & Johnson Clinical Diagnostics, Inc. (US) 1994-05-18 EP disclosed
US-4478992-A PHOTOGRAPHY EASTMAN KODAK COMPANY (US) 1984-10-23 US disclosed
US-4420630-A BINDERS FOR PHOTOGRAPHY EASTMAN KODAK COMPANY (US) 1983-12-13 US disclosed
US-4335254-A Polymerizable acryloyloxyarylenesulfonamides EASTMAN KODAK COMPANY (US) 1982-06-15 US disclosed
US-4289865-A USEFUL IN RELIEF IMAGES OR AS BINDERS IN PHOTOGRAPHIC MATERIALS EASTMAN KODAK COMPANY (US) 1981-09-15 US disclosed
US-4281207-A CROSSLINKING POLYMERS USEFUL IN RELIEF IMAGES, PHOTORESISTS, AND LITHOGRAPHIC PLATES EASTMAN KODAK COMPANY (US) 1981-07-28 US disclosed
US-4259469-A DESIRABLE SOLUBILITY CHARACTERISTICS FOR USE IN PHOTOLITHOGRAPHY EASTMAN KODAK COMPANY (US) 1981-03-31 US disclosed
US-4225689-A PHOTORESISTS, LITHOGRAPHIC PLATES, RELIF IMAGES EASTMAN KODAK COMPANY (US) 1980-09-30 US disclosed