Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6359120 | 0.82 | KMT2A (0.50) | KMT2AHTTP2RX3ALDH1A1MEN1 | |
| SCHEMBL6359121 | 0.82 | KMT2A (0.50) | KMT2AHTTP2RX3ALDH1A1MEN1 | |
| SCHEMBL4781020 | 0.77 | KMT2A (0.58) | KMT2AP2RX3MEN1P2RX7CYP2C9 | |
| SCHEMBL4781017 | 0.77 | KMT2A (0.58) | KMT2AP2RX3MEN1P2RX7CYP2C9 | |
| SCHEMBL11244923 | 0.75 | KMT2A (0.59) | KMT2AHTTP2RX3MEN1P2RX7 | |
| SCHEMBL2086875 | 0.75 | KMT2A (0.56) | KMT2AP2RX3ALDH1A1P2RX7HPGD | |
| SCHEMBL2086872 | 0.75 | KMT2A (0.56) | KMT2AP2RX3ALDH1A1P2RX7HPGD | |
| SCHEMBL11174716 | 0.74 | KMT2A (0.58) | KMT2AP2RX3ALDH1A1LMNACYP3A4 | |
| SCHEMBL7356086 | 0.74 | KMT2A (0.58) | KMT2AHTTP2RX3ALDH1A1MEN1 | |
| SCHEMBL8625066 | 0.74 | HTT (0.39) | KMT2AHTTALDH1A1MEN1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741708-B1 | CYANOGUANIDINES AS K-CHANNEL BLOCKERS | UPJOHN CO (US) | 1998-05-20 | — | — | EP | disclosed |
| US-5668157-A | Cyanoguanidines as K-channel blockers | PHARMACIA & UPJOHN COMPANY (US) | 1997-09-16 | — | — | US | disclosed |