Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | APLNR | P35414 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.36 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.34 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6359120 | 1.00 | KMT2A (0.50) | KMT2AAPLNRTDP1P2RX3P2RX7 | |
| SCHEMBL6361153 | 0.82 | KMT2A (0.49) | KMT2ATDP1P2RX3P2RX7IMPDH2 | |
| SCHEMBL8625067 | 0.82 | KMT2A (0.49) | KMT2ATDP1P2RX3P2RX7IMPDH2 | |
| SCHEMBL6361151 | 0.82 | KMT2A (0.49) | KMT2ATDP1P2RX3P2RX7IMPDH2 | |
| SCHEMBL2086872 | 0.81 | KMT2A (0.56) | KMT2AP2RX3P2RX7IMPDH2ALDH1A1 | |
| SCHEMBL2086875 | 0.81 | KMT2A (0.56) | KMT2AP2RX3P2RX7IMPDH2ALDH1A1 | |
| SCHEMBL4781017 | 0.78 | KMT2A (0.58) | KMT2AP2RX3P2RX7IMPDH2MEN1 | |
| SCHEMBL4781020 | 0.78 | KMT2A (0.58) | KMT2AP2RX3P2RX7IMPDH2MEN1 | |
| SCHEMBL11244923 | 0.76 | KMT2A (0.59) | KMT2AP2RX3P2RX7IMPDH2NPC1 | |
| SCHEMBL9954596 | 0.76 | KMT2A (0.56) | KMT2ATDP1P2RX3ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050239841-A1 | New compounds | BIOVITRUM AB (SE) | 2005-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050239841-A1 | New compounds | MCHR1, NPY1R, HCRTR1 | KMT2A 3307/4885APLNR 259/4885TDP1 3040/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.